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Association of cardiac autonomic modulation with physical and clinical features of young people with type 1 diabetes

Published online by Cambridge University Press:  16 March 2016

Anne K. F. Silva ,
Diego G. D. Christofaro ,
Franciele M. Vanderlei ,
Marianne P. C. R. Barbosa ,
David M. Garner  and
Luiz C. M. Vanderlei
Anne K. F. Silva
Affiliation:
Faculty of Science and Technology, Universidade Estadual Paulista, Presidente Prudente, São Paulo, Brazil
Diego G. D. Christofaro
Affiliation:
Department of Physical Education, Faculty of Science and Technology, Universidade Estadual Paulista, Presidente Prudente, São Paulo, Brazil
Franciele M. Vanderlei
Affiliation:
Department of Physical Therapy, Faculty of Science and Technology, Universidade Estadual Paulista, Presidente Prudente, São Paulo, Brazil
Marianne P. C. R. Barbosa
Affiliation:
Faculty of Science and Technology, Universidade Estadual Paulista, Presidente Prudente, São Paulo, Brazil
David M. Garner
Affiliation:
Cardiorespiratory Research Group, Department of Biological and Medical Sciences, Faculty of Health and Life Sciences, Oxford Brookes University, Oxford, United Kingdom
Luiz C. M. Vanderlei*
Affiliation:
Department of Physical Therapy, Faculty of Science and Technology, Universidade Estadual Paulista, Presidente Prudente, São Paulo, Brazil
*
Correspondence to: L. C. M. Vanderlei, Faculdade de Ciências e Tecnologia UNESP – Universidade Estadual Paulista, Programa de Pós Graduação em Fisioterapia, Avenida Roberto Simonsen, 305, 19060-900 Presidente Prudente, São Paulo, Brazil. Tel: +55 18 3229 5819; Fax: +55 18 3223 4519; E-mail: lcmvanderlei@fct.unesp.br
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Abstract

Objective

The objective of this study was to verify possible associations between heart rate variability indices and physical activity, body composition, and metabolic and cardiovascular parameters in individuals with type 1 diabetes.

Method

A total of 39 young patients with type 1 diabetes were included. Body composition, physical activity, cardiovascular parameters, and metabolic parameters were assessed. For the heart rate variability analysis, heart rate was recorded beat-by-beat using a Polar S810i heart rate monitor for 30 minutes, with the volunteers in the supine position; subsequently, the following indices were considered: standard deviation of all normal RR intervals; root-mean square of differences between adjacent normal RR intervals in a time interval; percentage of adjacent RR intervals with a difference of duration >50 ms; high frequency component in milliseconds squared; high frequency component in normalised units; standard deviation of the instantaneous variability beat-to-beat; and standard deviation of the long-term variability. The association between the heart rate variability indices and independent variables was verified through linear regression in unadjusted and adjusted models (considering gender and age). The statistical significance was set at 5% and the confidence interval at 95%.

Results

High values of at-rest heart rate were associated with reduced parasympathetic activity and global heart rate variability, and higher values of waist-to-hip ratio were related to lower parasympathetic activity, independent of age or gender.

Conclusion

For young patients with type 1 diabetes, increases in at-rest heart rate values are associated with reduced parasympathetic activity and global heart rate variability, whereas higher waist-to-hip ratio values are related to lower parasympathetic activity, both independent of age and gender.

Keywords

Diabetes mellitustype 1autonomic nervous systemrisk factorsheart rateyoung adult
Type
Original Articles
Information
Cardiology in the Young , Volume 27 , Issue 1 , January 2017 , pp. 37 - 45
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Copyright
© Cambridge University Press 2016 

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