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Catheter interventions in the staged management of hypoplastic left heart syndrome

Published online by Cambridge University Press:  08 February 2013

Zdenka Reinhardt ,
Joseph De Giovanni ,
John Stickley ,
Vinay K. Bhole ,
Benjamin Anderson ,
Bari Murtuza ,
Chetan Mehta ,
Paul Miller ,
Rami Dhillon  and
Oliver Stumper
Zdenka Reinhardt
Affiliation:
Department of Cardiology, Heart Unit, Birmingham Children's Hospital, NHS Foundation Trust, Birmingham, United Kingdom
Joseph De Giovanni
Affiliation:
Department of Cardiology, Heart Unit, Birmingham Children's Hospital, NHS Foundation Trust, Birmingham, United Kingdom
John Stickley
Affiliation:
Department of Cardiology, Heart Unit, Birmingham Children's Hospital, NHS Foundation Trust, Birmingham, United Kingdom
Vinay K. Bhole
Affiliation:
Department of Cardiology, Heart Unit, Birmingham Children's Hospital, NHS Foundation Trust, Birmingham, United Kingdom
Benjamin Anderson
Affiliation:
Department of Cardiology, Heart Unit, Birmingham Children's Hospital, NHS Foundation Trust, Birmingham, United Kingdom
Bari Murtuza
Affiliation:
Department of Cardiology, Heart Unit, Birmingham Children's Hospital, NHS Foundation Trust, Birmingham, United Kingdom
Chetan Mehta
Affiliation:
Department of Cardiology, Heart Unit, Birmingham Children's Hospital, NHS Foundation Trust, Birmingham, United Kingdom
Paul Miller
Affiliation:
Department of Cardiology, Heart Unit, Birmingham Children's Hospital, NHS Foundation Trust, Birmingham, United Kingdom
Rami Dhillon
Affiliation:
Department of Cardiology, Heart Unit, Birmingham Children's Hospital, NHS Foundation Trust, Birmingham, United Kingdom
Oliver Stumper*
Affiliation:
Department of Cardiology, Heart Unit, Birmingham Children's Hospital, NHS Foundation Trust, Birmingham, United Kingdom
*
Correspondence to: Dr O. Stumper, MD, PhD, Consultant Paediatric Cardiologist, Department of Paediatric Cardiology, Heart Unit, Birmingham Children's Hospital NHS Trust, Steelhouse Lane, Birmingham B6 4NH, United Kingdom. Tel: +44121 333 9999; Fax: +44121 333 9998; E-mail: oliver.stumper@bch.nhs.uk
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Abstract

Aim

To analyse the current practice and contribution of catheter interventions in the staged management of patients with hypoplastic left heart syndrome.

Methods

This study is a retrospective case note review of 527 patients undergoing staged Norwood/Fontan palliation at a single centre between 1993 and 2010. Indications and type of catheter interventions were reviewed over a median follow-up period of 7.5 years.

Results

A staged Norwood/Fontan palliation for hypoplastic left heart syndrome was performed in 527 patients. The 30-day survival rate after individual stages was 76.5% at Stage I, 96.3% at Stage II, and 99.4% at Stage III. A total of 348 interventions were performed in 189 out of 527 patients. Freedom from catheter intervention in survivors was 58.2% before Stage II and 46.7% before Stage III. Kaplan–Meier freedom from intervention post Fontan completion was 55% at 10.8 years of follow-up. Post-stage I interventions were mostly directed to relieve aortic arch obstruction – 84 balloon angioplasties – and augment pulmonary blood flow – 15 right ventricle-to-pulmonary conduit interventions; post-Stage II interventions centred on augmenting size of the left pulmonary artery – 73 procedures and abolishing systemic venous collaterals – 32 procedures. After Stage III, the focus was on manipulating the size of the fenestration – 42 interventions – and the left pulmonary artery −31 procedures.

Conclusion

Interventional cardiac catheterisation constitutes an integral part in the staged palliative management of patients with hypoplastic left heart syndrome. Over one-third (37%) of patients undergoing staged palliation required catheter intervention over the follow-up period.

Keywords

NorwoodFontanstentballoon dilation
Type
Original Articles
Information
Cardiology in the Young , Volume 24 , Issue 2 , April 2014 , pp. 212 - 219
Copyright
Copyright © Cambridge University Press 2013 

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