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Early Predictors of Sepsis in the Motor-Vehicle Crash Trauma Victim

Published online by Cambridge University Press:  28 June 2012

Jeanette K. Previdi ,
C. Gene Cayten  and
Daniel W. Byrne
Jeanette K. Previdi
Affiliation:
Institute for Trauma and Emergency Care, New York Medical College, Valhalla, New York
C. Gene Cayten*
Affiliation:
Institute for Trauma and Emergency Care, New York Medical College, Valhalla, New York
Daniel W. Byrne
Affiliation:
Institute for Trauma and Emergency Care, New York Medical College, Valhalla, New York
*
Institute for Trauma and Emergency Care, New York Medical College, Valhalla, NY 10595USA
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Abstract

Introduction:

Sepsis is a major cause of late morbidity and mortality in the victim of trauma. Currently, there is no method that is clinically practical and accurate for predicting the occurrence of sepsis in trauma victims.

Methods:

Data were collected on 3,759 motor-vehicle crash victims from 16 hospitals during a 4 1/2 year period. Retrospective analysis was done to examine the relationship of patient and injury factors known within the first 24 hours of admission on the development of sepsis.

Results:

Sepsis developed in 154 patients (4.1%) who had a mortality rate of 17.5% Significant early predictors of sepsis included: 1) certain pre-existing conditions; 2) blood transfusion required; 3) seven or more injuries; 4) Glasgow Coma Scale score <10 and hypertension; 5) major blood vessel injury; 6) head trauma; 7) internal injury of the chest or abdomen; 8) spinal-cord injury; and 9) certain fracture types.

Conclusions:

These predictors might help target high-risk patients and, thus, promote earlier and more effective treatment for those patients.

Keywords

infectioninjury typesmorbiditymortalitymotor-vehicle crashessepsisshocktransfusionstrauma
Type
Original Research
Information
Prehospital and Disaster Medicine , Volume 11 , Issue 1 , March 1996 , pp. 27 - 36
Copyright
Copyright © World Association for Disaster and Emergency Medicine 1996

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