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Luteinizing hormone secretion, ovulatory capacity, and oocyte quality in peripubertal Gir heifers

Published online by Cambridge University Press:  12 May 2023

Clara Slade Oliveira Open the ORCID record for Clara Slade Oliveira [Opens in a new window] ,
Paola Maria da Silva Rosa ,
Bruna Rios Coelho Alves Open the ORCID record for Bruna Rios Coelho Alves [Opens in a new window] ,
Clara Ana Santos Monteiro ,
Gabriela Ramos Leal Open the ORCID record for Gabriela Ramos Leal [Opens in a new window] ,
Pedro Henrique Evangelista Guedes ,
Agostinho Jorge dos Reis Camargo  and
Naiara Zoccal Saraiva Open the ORCID record for Naiara Zoccal Saraiva [Opens in a new window]
Clara Slade Oliveira*
Affiliation:
Embrapa Dairy Cattle, 610 Eugenio do Nascimento Ave, Juiz de Fora, MG, Brazil 36038-330
Paola Maria da Silva Rosa
Affiliation:
Embrapa Dairy Cattle, 610 Eugenio do Nascimento Ave, Juiz de Fora, MG, Brazil 36038-330
Bruna Rios Coelho Alves
Affiliation:
Universidade Federal Fluminense – UFF, Setor de Reprodução Animal, Rua Vital Brazil Filho, 64, Santa Rosa, Niteroi, RJ, Brazil 24230-340
Clara Ana Santos Monteiro
Affiliation:
Embrapa Dairy Cattle, 610 Eugenio do Nascimento Ave, Juiz de Fora, MG, Brazil 36038-330
Gabriela Ramos Leal
Affiliation:
Embrapa Dairy Cattle, 610 Eugenio do Nascimento Ave, Juiz de Fora, MG, Brazil 36038-330
Pedro Henrique Evangelista Guedes
Affiliation:
Embrapa Dairy Cattle, 610 Eugenio do Nascimento Ave, Juiz de Fora, MG, Brazil 36038-330
Agostinho Jorge dos Reis Camargo
Affiliation:
Agricultural Research Company of the Rio de Janeiro State (PESAGRO-RIO), São Boa Ventura Av., 770, Fonseca, Niteroi, Rio de Janeiro, Brazil 24120-19
Naiara Zoccal Saraiva
Affiliation:
Embrapa Dairy Cattle, 610 Eugenio do Nascimento Ave, Juiz de Fora, MG, Brazil 36038-330
*
Author for correspondence: Clara Slade Oliveira, Embrapa Dairy Cattle, 610 Eugenio do Nascimento Ave, Juiz de Fora, MG, Brazil 36038-330. E-mail: clara.oliveira@embrapa.br
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Summary

Induction of puberty in cattle breeds that attain puberty in later stages, such as Gir, allows the earlier beginning of reproductive life and it might increase oocyte quality. Here, the ovulatory capacity of prepuberal Gir heifers was studied and its relationship to follicular growth, luteinizing hormone (LH) secretion and oocyte quality was evaluated. Peripubertal Gir heifers were treated with a progesterone-based protocol and according to ovulatory response were separated into groups: not-ovulated (N-OV) and ovulated (OV). Serial blood samples were taken 24 h after estradiol treatment on day 12 to evaluate LH secretion. Cumulus–oocyte complexes (COCs) were collected using ovum pick-up and assessed for brilliant cresyl blue (BCB) staining rate, IVF-grade oocytes rate, and mean oocyte diameter, in comparison with cow oocytes. Gene expression of developmental competence markers (ZAR1, MATER, and IGF2R) was also analyzed. The largest follicle diameters were similar between N-OV and OV groups on the day of estradiol treatment (d12) and the next day and decreased (P = 0.04) in the N-OV group thereafter. LH pulse secretion was different between groups (N-OV = 3.61 ± 0.34 vs OV = 2.83 ± 0.21 ng/ ml; P = 0.04). COC assessment showed that the number of recovered oocytes, BCB+ rate, IVF-grade oocytes and oocyte size was similar (P > 0.05) among groups, resembling adult cow patterns. ZAR1, MATER and IGF2R gene expression in oocytes were also similar (P > 0.05) in N-OV and OV groups. In conclusion, our results demonstrate a lower LH secretion profile in peripubertal Gir heifers prone to ovulate after induction protocol, and that oocyte quality is not affected on a short-term basis by ovulation itself.

Keywords

BCB stainingCOC diameterLuteinizing hormone pulsatilityOocyte competenceOocyte gene expressionPuberty
Type
Research Article
Information
Zygote , Volume 31 , Issue 4 , August 2023 , pp. 342 - 349
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Copyright
© The Author(s), 2023. Published by Cambridge University Press

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Footnotes

†

Clara Slade Oliveira and Paola Maria da Silva Rosa are joint first authors.

References

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