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VIII.44 - Eclampsia

from Part VIII - Major Human Diseases Past and Present

Published online by Cambridge University Press:  28 March 2008

Kenneth F. Kiple
Affiliation:
Bowling Green State University, Ohio
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Summary

Eclampsia is a puzzling hypertensive disorder affecting only women. Associated solely with pregnancy and childbirth, it is an epileptic form of convulsions that develops during the second half of pregnancy and disappears after conception. The severity depends upon the degree and timing of the illness as well as the characteristics of the patient. Eclampsia is associated with hypertension, edema, and toxemia, and all three can cause the symptoms of the disease to vary widely. Preeclampsia refers to hypertension, abnormal edema, or proteinuria during pregnancy, whereas eclampsia is the disease’s most extreme form, manifested by severe convulsions, coma, and even death. Eclampsia is a leading cause of maternal and fetal mortality and can cause stillbirths or premature labor. Medical experts remain confused about the cause of this disorder and have no effective way to cure the disease other than to terminate pregnancy by delivering the baby. Through careful prenatal care, however, physicians can usually control the problem, and it is now relatively rare in the United States and Europe.

Not only is the disease difficult to define, but also accurate records of its existence are rare, especially in Third World countries where prenatal care by a medical attendant is uncommon. Although eclampsia is one of the diseases most troubling to obstetricians, research on the illness is difficult because it is found only in human beings. Its etiology remains unknown but may be multifactorial.

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Publisher: Cambridge University Press
Print publication year: 1993

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References

Brewer, Thomas H. 1966. Metabolic toxemia of late pregnancy: A disease of malnutrition. Springfield, Ill..Google Scholar
Chesley, Leon C. 1981. Hypertensive disorders in pregnancy. New York.Google Scholar
Coudon, James. 1813. An inaugural essay on eclampsia or puerperal convulsions. Baltimore.Google Scholar
Davies, A. Michael. 1971. Geographical epidemiology of the toxemias of pregnancy. Springfield, Ill..Google ScholarPubMed
Denman, Thomas. 1768. Essays on the puerperal fever and on puerperal convulsions. London.Google Scholar
Dieckmann, William Joseph. 1952. The toxemias of pregnancy, 2d edition. St. Louis.Google Scholar
International Society for the Study of Hypertension in Pregnancy and Pregnancy Hypertension. 1980. Proceedings of the First Congress of the International Society, ed. Bonner, John, Ian Macgillivray, and Malcolm Symond. Baltimore.Google Scholar
Kitzmiller, John. 1977. Immunologic approaches to the study of preeclampsia. Clinical Obstetrics and Gynecology 20, 3.Google Scholar
MacGillivrary, Ian. 1983. Pre-eclampsia: The hypertensive disease of pregnancy. New York.Google Scholar
Pritchard, J. A., ed. 1985. Hypertensive disorders in pregnancy. In Williams’ obstetrics, 17th edition, 525–60. Norwalk, Conn..Google Scholar
Slocomb, John C., and Kunitz, Stephen J.. 1977. Factors affecting maternal mortality and morbidity among American Indians. Public Health Reports No. 92. Washington, D.C..Google Scholar
Williams, Richard Allen, ed. 1975. Textbook of blackrelated diseases. New York.Google Scholar

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  • Eclampsia
  • Edited by Kenneth F. Kiple, Bowling Green State University, Ohio
  • Book: The Cambridge World History of Human Disease
  • Online publication: 28 March 2008
  • Chapter DOI: https://doi.org/10.1017/CHOL9780521332866.106
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  • Eclampsia
  • Edited by Kenneth F. Kiple, Bowling Green State University, Ohio
  • Book: The Cambridge World History of Human Disease
  • Online publication: 28 March 2008
  • Chapter DOI: https://doi.org/10.1017/CHOL9780521332866.106
Available formats
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Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

  • Eclampsia
  • Edited by Kenneth F. Kiple, Bowling Green State University, Ohio
  • Book: The Cambridge World History of Human Disease
  • Online publication: 28 March 2008
  • Chapter DOI: https://doi.org/10.1017/CHOL9780521332866.106
Available formats
×