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VIII.48 - Epilepsy

from Part VIII - Major Human Diseases Past and Present

Published online by Cambridge University Press:  28 March 2008

Kenneth F. Kiple
Affiliation:
Bowling Green State University, Ohio
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Summary

Epilepsy is characterized by the repeated occurrence of seizures that result from recurrent, abnormal, excessive, synchronous discharges of populations of cerebral neurons (Epilepsy Foundation of America 1981). It has a worldwide distribution and probably has been in existence since the dawn of human history. The condition is chronic but rarely fatal, and most types of epilepsy do not disturb the affected individual’s desire or ability to lead a normal life. Modern antiepileptic medications most often control seizures, and the limitations imposed by the disorder may be negligible. Unfortunately, epileptics are all too frequently stigmatized and excluded from many activities of daily life. Outdated beliefs and misconceptions about epilepsy have only recently shown signs of lessening in the United States and other industrialized societies.

It is misleading to think of epilepsy as one disease. There are many causes of this symptom cluster, just as there are for the symptom cluster of nausea and vomiting. A better term would be “the epilepsies.” The epilepsies do, however, share certain physiological characteristics. Clusters of neurons in some parts of the brain begin to discharge impulses in a disorganized fashion. The parts of the body controlled by the affected neurons respond with disorganized activity such as convulsions or tremors, or by loss of normal function such as loss of consciousness, paralysis of a limb, or localized numbness. The condition is also chronic, marked by the recurrence of seizures. By monitoring the brain with electrodes, an electroencephalographer can often detect abnormal brain waves, either localized in one part of the brain or coming from all parts at once.

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Publisher: Cambridge University Press
Print publication year: 1993

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References

,Epilepsy Foundations of America. 1981. How to recognize and classify seizures. Landover, Maryland: Epilepsy Foundation of America.
Ervin, Frank R. 1967. Brain disorders. IV: Associated with convulsions (epilepsy). In Comprehensive textbook of psychiatry, ed. Freedman, Alfred M. and Kaplan, Harold I.. Baltimore.Google Scholar
Hauser, W. Allen, and Kurland, Leonard T.. 1975. The epidemiology of epilepsy in Rochester, Minnesota, 1935 through 1967. Epilepsia 16.CrossRefGoogle ScholarPubMed
Koul, Roshan, Razdan, S., and Motta, Anil. 1988. Prevalence and pattern of epilepsy (Lath/Mirgi/Laran) in rural Kashmir, India. Epilepsia 29.CrossRefGoogle ScholarPubMed
Kurland, Leonard T. 1949. The incidence and prevalence of convulsive disorders in a small urban community. Epilepsia 1.Google Scholar
Kurland, Leonard T., Kurtzke, John F., and Goldberg, Irving D.. 1973. Epidemiology of neurologic and sense organ disorders. Cambridge.Google Scholar
Lechtenberg, Richard. 1984. Epilepsy and the family. Cambridge.Google Scholar
Levy, Jerrold E., Neutra, Raymond, and Parker, Dennis. 1987. Hand trembling, frenzy witchcraft, and moth madness: A study of Navajo seizure disorders. Tucson.Google Scholar
Temkin, Owsei. 1971. The falling sickness: A history of epilepsy from the Greeks to the beginnings of modern neurology, 2d edition. Baltimore.Google Scholar
Tsuboi, Takayuki 1988. Prevalence and incidence of epilepsy in Tokyo. Epilepsia 29.CrossRefGoogle ScholarPubMed

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  • Epilepsy
  • Edited by Kenneth F. Kiple, Bowling Green State University, Ohio
  • Book: The Cambridge World History of Human Disease
  • Online publication: 28 March 2008
  • Chapter DOI: https://doi.org/10.1017/CHOL9780521332866.110
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  • Epilepsy
  • Edited by Kenneth F. Kiple, Bowling Green State University, Ohio
  • Book: The Cambridge World History of Human Disease
  • Online publication: 28 March 2008
  • Chapter DOI: https://doi.org/10.1017/CHOL9780521332866.110
Available formats
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Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

  • Epilepsy
  • Edited by Kenneth F. Kiple, Bowling Green State University, Ohio
  • Book: The Cambridge World History of Human Disease
  • Online publication: 28 March 2008
  • Chapter DOI: https://doi.org/10.1017/CHOL9780521332866.110
Available formats
×