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Chapter 39 - Acute Management of Sepsis in Pregnancy

from Section 4 - Maternal Medicine

Published online by Cambridge University Press:  20 November 2021

Tahir Mahmood
Affiliation:
Victoria Hospital, Kirkcaldy
Charles Savona Ventura
Affiliation:
University of Malta, Malta
Ioannis Messinis
Affiliation:
University of Thessaly, Greece
Sambit Mukhopadhyay
Affiliation:
Norfolk & Norwich University Hospital, UK
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Summary

Sepsis is the body’s life-threatening response to severe infection. Classification of sepsis is currently based on mortality and amount of organ dysfunction as defined by the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3) [1]. The World Health Organization (WHO) has added to these to incorporate the definition of maternal sepsis [2] as described in Table 39.1.

Type
Chapter
Information
The EBCOG Postgraduate Textbook of Obstetrics & Gynaecology
Obstetrics & Maternal-Fetal Medicine
, pp. 329 - 336
Publisher: Cambridge University Press
Print publication year: 2021

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References

Singer, M, Deutschman, CS, Seymour, CW, et al. The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). JAMA. 2016 Feb 23;315(8):801–10Google Scholar
World Health Organization (WHO). Statement of Maternal Sepsis. 2017. WHO/RHR/17.02Google Scholar
Knight, M, Bunch, K, Tuffnell, D, et al, eds., on behalf of MBRRACE-UK.Saving Lives, Improving Mothers’ Care: Lessons Learned to Inform Maternity Care from the UK and Ireland Confidential Enquiries into Maternal Deaths and Morbidity 2014–16. Oxford: National Perinatal Epidemiology Unit, University of Oxford; 2018.Google Scholar
Stearns-Kurosawa, D, Osuchowski, M, Valentine, C, Kurosawa, S, Remick, DG. The pathogenesis of sepsis. Annu Rev Pathol. 2011;6(1):1948.CrossRefGoogle ScholarPubMed
Bacterial Sepsis in Pregnancy and Bacterial Sepsis Following Pregnancy, Green-top Guidelines Nos 64a and 64b. London: Royal College of Obstetricians and Gynaecologists, April 2012.Google Scholar
Prevention of Early-onset Neonatal Group B Streptococcal Disease, Green-top Guideline No 36. London: Royal College of Obstetricians and Gynaecologists, September 2017.Google Scholar
Zuarez-Easton, S, Zafran, N, Garmi, G, Salim, R. Postcesarean wound infection: prevalence, impact, prevention, and management challenges. Int J Womens Health. 2017;9:81–8.CrossRefGoogle ScholarPubMed
Royal College of Physicians. National Early Warning Score (NEWS): Standardising the Assessment of Acute‐Illness Severity in the NHS. London: RCP; 2012Google Scholar
Protection of Pregnant Patients during Diagnostic Medical Exposures to Ionising Radiation. Health Protection Agency and Royal College of Radiologists; 2009. www.rcr.ac.uk/publication/protection-pregnant-patients-during-diagnostic-medical-exposures-ionising-radiationGoogle Scholar
Doyle, L, Crowther, CA, Middleton, P, Marret, S. Magnesium sulphate for women at risk of preterm birth for neuroprotection of the fetus. Cochrane Database Syst Rev. 2009;(1):CD004661Google Scholar
NICE. Ectopic Pregnancy and Miscarriage: Diagnosis and Initial Management. Clinical Guideline 154. 2012. www.nice.org.uk/guidance/CG154Google Scholar
Public Health England. Hand Hygiene Audit Tool for Care Homes. www.infectionpreventioncontrol.co.uk/resources/hand-hygiene/Google Scholar
Kenyon, S, Pike, K, Jones, DR. Childhood outcomes following prescription of antibiotics to pregnant women with preterm rupture of the membranes: 7-year follow-up of the Oracle I trial. Lancet. 2008;372:1310–18.Google ScholarPubMed
Kenyon, S, Pike, K, Jones, DR. Childhood outcomes following prescription of antibiotics to pregnant women with spontaneous preterm labour: 7-year follow-up of the Oracle II trial. Lancet. 2008;372:1319–27.Google ScholarPubMed
NICE. Inducing Labour. Clinical Guideline 70. 2008. www.nice.org.uk/guidance/cg70/chapter/1-guidanceGoogle Scholar
Royal College of Emergency Medicine and the UK Sepsis Trust. Sepsis: A Toolkit for Emergency Departments. 2014. www.rcem.ac.uk/docs/Sepsis/Sepsis%20Toolkit.pdfGoogle Scholar
Dellinger, RP, Levy, MM, Rhodes, A, et al; Surviving Sepsis Campaign Guidelines Committee Including the Pediatric Subgroup. Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2012. Crit Care Med. 2013;41(2):580637.Google Scholar

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