Book contents
- Frontmatter
- Contents
- CONTRIBUTORS
- PREFACE
- Chap. 1 CELL INJURY AND CELL DEATH
- Chap. 2 CLEAN AND ASEPTIC TECHNIQUE AT THE BEDSIDE
- Chap. 3 NEW ANTIMICROBIALS
- Chap. 4 IMMUNOMODULATORS AND THE “BIOLOGICS” IN CUTANEOUS EMERGENCIES
- Chap. 5 CRITICAL CARE: STUFF YOU REALLY, REALLY NEED TO KNOW
- Chap. 6 ACUTE SKIN FAILURE: CONCEPT, CAUSES, CONSEQUENCES, AND CARE
- Chap. 7 CUTANEOUS SYMPTOMS AND NEONATAL EMERGENCIES
- Chap. 8 NECROTIZING SOFT-TISSUE INFECTIONS, INCLUDING NECROTIZING FASCIITIS
- Chap. 9 LIFE-THREATENING BACTERIAL SKIN INFECTIONS
- Chap. 10 BACTEREMIA, SEPSIS, SEPTIC SHOCK, AND TOXIC SHOCK SYNDROME
- Chap. 11 STAPHYLOCOCCAL SCALDED SKIN SYNDROME
- Chap. 12 LIFE-THREATENING CUTANEOUS VIRAL DISEASES
- Chap. 13 LIFE-THREATENING CUTANEOUS FUNGAL AND PARASITIC DISEASES
- Chap. 14 LIFE-THREATENING STINGS, BITES, AND MARINE ENVENOMATIONS
- Chap. 15 SEVERE, ACUTE ADVERSE CUTANEOUS DRUG REACTIONS I: STEVENS–JOHNSON SYNDROME AND TOXIC EPIDERMAL NECROLYSIS
- Chap. 16 SEVERE, ACUTE ADVERSE CUTANEOUS DRUG REACTIONS II: DRESS SYNDROME AND SERUM SICKNESS-LIKE REACTION
- Chap. 17 SEVERE, ACUTE COMPLICATIONS OF DERMATOLOGIC THERAPIES
- Chap. 18 SEVERE, ACUTE ALLERGIC AND IMMUNOLOGICAL REACTIONS I: URTICARIA, ANGIOEDEMA, MASTOCYTOSIS, AND ANAPHYLAXIS
- Chap. 19 SEVERE, ACUTE ALLERGIC AND IMMUNOLOGICAL REACTIONS II: OTHER HYPERSENSITIVITIES AND IMMUNE DEFECTS, INCLUDING HIV
- Chap. 20 GRAFT VERSUS HOST DISEASE
- Chap. 21 ERYTHRODERMA/EXFOLIATIVE DERMATITIS
- Chap. 22 ACUTE, SEVERE BULLOUS DERMATOSES
- Chap. 23 EMERGENCY MANAGEMENT OF PURPURA AND VASCULITIS, INCLUDING PURPURA FULMINANS
- Chap. 24 EMERGENCY MANAGEMENT OF CONNECTIVE TISSUE DISORDERS AND THEIR COMPLICATIONS
- Chap. 25 SKIN SIGNS OF SYSTEMIC INFECTIONS
- Chap. 26 SKIN SIGNS OF SYSTEMIC NEOPLASTIC DISEASES AND PARANEOPLASTIC CUTANEOUS SYNDROMES
- Chap. 27 BURN INJURY
- Chap. 28 EMERGENCY DERMATOSES OF THE ANORECTAL REGIONS
- Chap. 29 EMERGENCY MANAGEMENT OF SEXUALLY TRANSMITTED DISEASES AND OTHER GENITOURETHRAL DISORDERS
- Chap. 30 EMERGENCY MANAGEMENT OF ENVIRONMENTAL SKIN DISORDERS: HEAT, COLD, ULTRAVIOLET LIGHT INJURIES
- Chap. 31 ENDOCRINOLOGIC EMERGENCIES IN DERMATOLOGY
- Chap. 32 EMERGENCY MANAGEMENT OF SKIN TORTURE AND SELF-INFLICTED DERMATOSES
- Chap. 33 SKIN SIGNS OF POISONING
- Chap. 34 DISASTER PLANNING: MASS CASUALTY MANAGEMENT
- Chap. 35 CATASTROPHES IN COSMETIC PROCEDURES
- Chap. 36 LIFE-THREATENING DERMATOSES IN TRAVELERS
- Index
- References
Chap. 11 - STAPHYLOCOCCAL SCALDED SKIN SYNDROME
Published online by Cambridge University Press: 07 September 2011
- Frontmatter
- Contents
- CONTRIBUTORS
- PREFACE
- Chap. 1 CELL INJURY AND CELL DEATH
- Chap. 2 CLEAN AND ASEPTIC TECHNIQUE AT THE BEDSIDE
- Chap. 3 NEW ANTIMICROBIALS
- Chap. 4 IMMUNOMODULATORS AND THE “BIOLOGICS” IN CUTANEOUS EMERGENCIES
- Chap. 5 CRITICAL CARE: STUFF YOU REALLY, REALLY NEED TO KNOW
- Chap. 6 ACUTE SKIN FAILURE: CONCEPT, CAUSES, CONSEQUENCES, AND CARE
- Chap. 7 CUTANEOUS SYMPTOMS AND NEONATAL EMERGENCIES
- Chap. 8 NECROTIZING SOFT-TISSUE INFECTIONS, INCLUDING NECROTIZING FASCIITIS
- Chap. 9 LIFE-THREATENING BACTERIAL SKIN INFECTIONS
- Chap. 10 BACTEREMIA, SEPSIS, SEPTIC SHOCK, AND TOXIC SHOCK SYNDROME
- Chap. 11 STAPHYLOCOCCAL SCALDED SKIN SYNDROME
- Chap. 12 LIFE-THREATENING CUTANEOUS VIRAL DISEASES
- Chap. 13 LIFE-THREATENING CUTANEOUS FUNGAL AND PARASITIC DISEASES
- Chap. 14 LIFE-THREATENING STINGS, BITES, AND MARINE ENVENOMATIONS
- Chap. 15 SEVERE, ACUTE ADVERSE CUTANEOUS DRUG REACTIONS I: STEVENS–JOHNSON SYNDROME AND TOXIC EPIDERMAL NECROLYSIS
- Chap. 16 SEVERE, ACUTE ADVERSE CUTANEOUS DRUG REACTIONS II: DRESS SYNDROME AND SERUM SICKNESS-LIKE REACTION
- Chap. 17 SEVERE, ACUTE COMPLICATIONS OF DERMATOLOGIC THERAPIES
- Chap. 18 SEVERE, ACUTE ALLERGIC AND IMMUNOLOGICAL REACTIONS I: URTICARIA, ANGIOEDEMA, MASTOCYTOSIS, AND ANAPHYLAXIS
- Chap. 19 SEVERE, ACUTE ALLERGIC AND IMMUNOLOGICAL REACTIONS II: OTHER HYPERSENSITIVITIES AND IMMUNE DEFECTS, INCLUDING HIV
- Chap. 20 GRAFT VERSUS HOST DISEASE
- Chap. 21 ERYTHRODERMA/EXFOLIATIVE DERMATITIS
- Chap. 22 ACUTE, SEVERE BULLOUS DERMATOSES
- Chap. 23 EMERGENCY MANAGEMENT OF PURPURA AND VASCULITIS, INCLUDING PURPURA FULMINANS
- Chap. 24 EMERGENCY MANAGEMENT OF CONNECTIVE TISSUE DISORDERS AND THEIR COMPLICATIONS
- Chap. 25 SKIN SIGNS OF SYSTEMIC INFECTIONS
- Chap. 26 SKIN SIGNS OF SYSTEMIC NEOPLASTIC DISEASES AND PARANEOPLASTIC CUTANEOUS SYNDROMES
- Chap. 27 BURN INJURY
- Chap. 28 EMERGENCY DERMATOSES OF THE ANORECTAL REGIONS
- Chap. 29 EMERGENCY MANAGEMENT OF SEXUALLY TRANSMITTED DISEASES AND OTHER GENITOURETHRAL DISORDERS
- Chap. 30 EMERGENCY MANAGEMENT OF ENVIRONMENTAL SKIN DISORDERS: HEAT, COLD, ULTRAVIOLET LIGHT INJURIES
- Chap. 31 ENDOCRINOLOGIC EMERGENCIES IN DERMATOLOGY
- Chap. 32 EMERGENCY MANAGEMENT OF SKIN TORTURE AND SELF-INFLICTED DERMATOSES
- Chap. 33 SKIN SIGNS OF POISONING
- Chap. 34 DISASTER PLANNING: MASS CASUALTY MANAGEMENT
- Chap. 35 CATASTROPHES IN COSMETIC PROCEDURES
- Chap. 36 LIFE-THREATENING DERMATOSES IN TRAVELERS
- Index
- References
Summary
STAPHYLOCOCCAL scalded skin syndrome (SSSS) is the term used to define a potentially life-threatening, blistering skin disease caused by exfoliative toxins (ETs) of certain strains of Staphylococcus aureus. The syndrome belongs to a wide spectrum of staphylococcal infections that range in severity from localized bullous impetigo to a generalized cutaneous involvement characterized by extensive blistering with superficial denudation and subsequent desquamation of the skin. SSSS is so-named because of its staphylococcal etiology and its remarkable resemblance to the clinical picture of scalding.
HISTORY
The original description of the syndrome dates back to 1878, when Ritter von Rittershain, director of an orphanage in Prague, reported approximately 300 cases of dermatitis exfoliativa neonatorum. A relationship between the disease and staphylococci was perceived at the beginning of the 20th century, but only in the early 1950s did the link between bullous impetigo and phage group 2 staphylococci become evident. Lyell's report on toxic epidermal necrolysis (TEN) in 1956 drew attention to the similarities between this drug-induced condition and the appearance of extensive scalding, but also led to a period of confusion between nonbacterial (immune-mediated) TEN and bacterial (staphylococcal) toxin-mediated scalded skin syndrome. In the early 1970s, the development of a murine model of the staphylococcal disease clarified the situation.
Nowadays, SSSS is clearly distinguished from other diseases of generalized epidermal necrolysis and the term Ritter's disease is still used to describe generalized SSSS in newborns.
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- Emergency Dermatology , pp. 109 - 114Publisher: Cambridge University PressPrint publication year: 2011