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8 - The origin of life: a review of facts and speculation

Published online by Cambridge University Press:  10 November 2010

Mark A. Bedau
Affiliation:
Reed College, Oregon
Carol E. Cleland
Affiliation:
University of Colorado, Boulder
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Summary

The problem of the origin of life on the Earth has much in common with a well-constructed detective story. There is no shortage of clues pointing to the way in which the crime, the contamination of the pristine environment of the early Earth, was committed. On the contrary, there are far too many clues and far too many suspects. It would be hard to find two investigators who agree on even the broad outline of the events that occurred so long ago and made possible the subsequent evolution of life in all its variety. Here, I outline two of the main questions and some of the conflicting evidence that has been used in attempts to answer them. First, however, I summarize the few areas where there is fairly general agreement.

The Earth is slightly more than 4.5 billion years old. For the first half billion years or so after its formation, it was impacted by objects large enough to evaporate the oceans and sterilize the surface. Well-preserved microfossils of organisms that have morphologies similar to those of modern blue-green algae, and date back about 3.5 billion years, have been found, and indirect but persuasive evidence supports the proposal that life was present 3.8 billion years ago. Life, therefore, originated on or was transported to the Earth at some point within a window of a few hundred million years that opened about four billion years ago.

Type
Chapter
Information
The Nature of Life
Classical and Contemporary Perspectives from Philosophy and Science
, pp. 121 - 128
Publisher: Cambridge University Press
Print publication year: 2010

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References

Sleep, N. H., Zahnle, K. J., Kasting, J. F., & Morowitz, H. J. (1989). Annihilation of ecosystems by large asteroid impacts on early Earth. Nature, 342, 139–142.CrossRefGoogle ScholarPubMed
Chyba, C. F. (1993). The violent environment of the origin of life: Progress and uncertainties. Geochimica et Cosmochimica Acta, 57, 3351–3358.CrossRefGoogle Scholar
Schopf, J. W. (1993). The Earth's earliest biosphere: Its origin and evolution. Princeton, NJ: Princeton University Press.Google Scholar
Mojzsis, S. J., Arrhenius, G., McKeegan, K. D., Harrison, T. M., Nutman, A. P., & Friend, C. R. (1996). Evidence for life on Earth before 3,800 million years ago. Nature, 384, 55–59.CrossRefGoogle ScholarPubMed
Feng, D.-F., Cho, G., & Doolittle, R. F. (1997). Determining divergence times with a protein clock: Update and reevaluation. Proceedings of the National Academy of Sciences, 94, 13,028–13,033.CrossRefGoogle ScholarPubMed
Miller, S. L. (1953). A production of amino acids under possible primitive Earth conditions. Science, 117, 528–529.CrossRefGoogle ScholarPubMed
Ring, D., Wolman, Y., Friedmann, N., & Miller, S. L. (1972). Prebiotic synthesis of hydrophobic and protein amino acids. Proceedings of the National Academy of Sciences, 69, 765–768.CrossRefGoogle ScholarPubMed
Wolman, Y., Haverland, H., & Miller, S. L. (1972). Nonprotein amino acids from spark discharges and their comparison with the Murchison meteorite amino acids. Proceedings of the National Academy of Sciences, 69, 809–811.CrossRefGoogle ScholarPubMed
Oro, J. (1960). Synthesis of adenine from ammonium cyanide. Biochemical and Biophysical Research Communications, 2, 407–412.CrossRefGoogle Scholar
Ferris, J. P., Sanchez, A., & Orgel, L. E. (1968). Studies in prebiotic synthesis III. Synthesis of pyrimidines from cyanoacetylene and cyanate. Journal of Molecular Biology, 33, 693–704.CrossRefGoogle Scholar
Butlerow, A. (1861). Formation synthétique d'une substance sucrée. Comptes Rendus de l' Académie des Sciences, 53, 145–147.Google Scholar
Butlerow, A. (1861). Bildung einer zuckerartingen Substanz durch Synthese. Justus Liebigs Annalen der Chemie, 120, 295–298.CrossRefGoogle Scholar
Kasting, J. F. (1993). Earth's early atmosphere. Science, 259, 920–926.CrossRefGoogle ScholarPubMed
Cronin, J. R., Pizzarella, S., & Crukshank, D. P. (1988). Organic matter in carbonaceous chondrites, planetary satellites, asteroids and comets. In Kerridge, J. F. & Matthew, M. S. (Eds.), Meteorites and the early solar system (pp. 819–857). Tuscan, AZ: University of Arizona Press.Google Scholar
Chyba, C. & Sagan, C. (1992). Endogenous production, exogenous delivery and impact-shock synthesis of organic molecules: An inventory for the origins of life. Nature, 355, 125–132.CrossRefGoogle ScholarPubMed
Wächtershäuser, G. (1988). Before enzymes and templates: Theory of surface metabolism. Microbiological Reviews, 52, 452–484.Google ScholarPubMed
Wächtershäuser, G. (1992). Groundworks for an evolutionary biochemistry: The iron-sulfur world. Progress in Biophysics and Molecular Biology, 58, 85–201.CrossRefGoogle Scholar
Blöchl, E., Keller, M., Wächtershäuser, G., & Stetter, K. O. (1992). Reactions depending on iron sulfide and linking geochemistry with biochemistry. Proceedings of the National Academy of Sciences, 89, 8117–8120.CrossRefGoogle ScholarPubMed
Huber, C. & Wächtershäuser, G. (1997). Activated acetic acid by carbon fixation on (Fe,Ni)S under primordial conditions. Science, 276, 245–247.CrossRefGoogle ScholarPubMed
Gesteland, R. F. & Atkins, J. F. (1993). The RNA world: The nature of modern RNA suggests a prebiotic world. Long Island, NY: Cold Spring Harbor Laboratory Press.Google Scholar
Pan, T. (1997). Novel and variant ribozymes obtained through in vitro selection. Current Opinion in Chemical Biology, 1, 17–25.CrossRefGoogle ScholarPubMed
Breaker, R. R. (1997). DNA aptamers and DNA enzymes. Current Opinion in Chemical Biology, 1, 26–31.CrossRefGoogle ScholarPubMed
Eklund, E. H., Szostak, J. W., & Battel, D. P. (1995). Structurally complex and highly active RNA ligases derived from random RNA sequences. Science, 269, 364–370.CrossRefGoogle Scholar
Eklund, E. H. & Bartel, D. P. (1996). RNA-catalysed RNA polymerization using nucleoside triphosphates. Nature, 382, 373–376.CrossRefGoogle Scholar
Unrau, P. J. & Bartel, D. P. (1998). RNA-catalysed nucleotide synthesis. Nature, 395, 260–263.CrossRefGoogle ScholarPubMed
Ferris, J. P. & Ertem, G. (1993). Montmorillonite catalysis of RNA oligomer formation in aqueous solution: A model for the prebiotic formation of RNA. Journal of the American Chemical Society, 115, 12,270–12,275.CrossRefGoogle ScholarPubMed
Kawamura, K. & Ferris, J. P. (1994). Kinetic and mechanistic analysis of dinucleotide and oligonucleotide formation from the 5′-phosphorimidazolide of adenosine on NA+-montmorillonite. Journal of the American Chemical Society, 119, 7564–7572.CrossRefGoogle Scholar
Hill, A. R., Wu, T., & Orgel, L. E. (1993). The limits of template-directed synthesis with nucleoside-5′-phosphoro(2-methyl)imidazolides. Origins of Life and Evolution of the Biosphere, 23, 285–290.CrossRefGoogle ScholarPubMed
Orgel, L. E. (1994). The origin of life on Earth. Scientific American, 271, 52–61.CrossRefGoogle Scholar
Ferris, J. P. (1987). Prebiotic synthesis: Problems and challenges. Cold Spring Harbor Symposia on Quantitative Biology, LII, 29–39.CrossRefGoogle Scholar
Joyce, G. F., Visser, G. M., Boeckel, A. A., Boom, J. H., Orgel, L. E., & Westrenen, J. (1984). Nature, 310, 602–604.CrossRef
Müller, D., Pitsch, S., Kittaka, A., et al. (1990). Chimie von a-Aminonitrilen. Aldomerisierung von Glycolaldehyd-phosphat zu racemischen Hexose-2,4,6-triphosphaten und (in Gegenwart von Formaldehyd) racemischen Pentose-2,4-diphosphaten: Rac-Allose-2,4,6-triphosphat und rac-Ribose-2,4-diphosphat sind die Reaktionshauptprodukte. Helvetica Chimica Acta, 73, 1410–1463.CrossRefGoogle Scholar
Cairns-Smith, A. G. (1982). Genetic takeover and the mineral origins of life. Cambridge, UK: Cambridge University Press.Google Scholar
Cairns-Smith, A. G. & Davis, C. J. (1997). The design of novel replicating polymers. In Duncan, R. and Weston-Smith, M. (Eds.), Encyclopaedia of ignorance (pp. 397–403). New York: Pergamon Press.Google Scholar
Eschenmoser, A. (1997). Towards a chemical etiology of nucleic acid structure. Origins of Life and Evolution of the Biospheres, 27, 535–553.CrossRefGoogle ScholarPubMed
Egholm, M., Buchardt, O., Nielsen, P. E., & Berg, R. H. (1992). Peptide of nucleic acids (PNA): Oligonucleotide analogs with an achiral peptide backbone. Journal of the American Chemical Society, 114, 1895–1897.CrossRefGoogle Scholar
Egholm, M., Buchardt, O., Christensen, L., et al. (1993). PNA hybridizes to complementary oligonucleotides obeying the Watson-Crick hydrogen-bonding rules. Nature, 365, 566–568.CrossRefGoogle ScholarPubMed
Schmidt, J. G., Nielsen, P. E., & Orgel, L. E. (1997). Information transfer from DNA to peptide nucleic acids by template-directed syntheses. Nucleic Acids Research, 25, 4792–4796.CrossRefGoogle ScholarPubMed
Schmidt, J. G., Nielsen, P. E., & Orgel, L. E. (1997). Information transfer from peptide nucleic acids to RNA by template-directed synthesis. Nucleic Acids Research, 25, 4797–4802.CrossRefGoogle Scholar
Koppitz, M., Nielsen, P. E., & Orgel, L. E. (1998). Formation of oligonucleotide-PNA-chimeras by template-directed ligation. Journal of the American Chemical Society, 120, 4563–4569.CrossRefGoogle ScholarPubMed
Kauffman, S. A. (1986). Autocatalytic sets of proteins. Journal of Theoretical Biology, 119, 1–24.CrossRefGoogle ScholarPubMed
Wächtershäuser, G. (1988). Before enzymes and templates: Theory of surface metabolism. Microbiological Reviews, 52, 452–484.Google ScholarPubMed
Duve, C. (1991). Blueprint for a cell: The nature and origin of life. Burlington, NC: Neil Patterson.Google Scholar

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