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Case 15 - Lymphocytic interstitial pneumonia

Published online by Cambridge University Press:  07 October 2011

Thomas Hartman
Affiliation:
Mayo Clinic, Rochester
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Summary

Imaging description

The primary imaging findings of lymphocytic interstitial pneumonia (LIP) are bilateral regions of ground-glass opacity [1, 2]. These are most often diffuse, but may be patchy in distribution. Most patients will also have poorly defined centrilobular nodules. Thickening of interlobular septa and bronchovascular bundles is present in 80% of patients. Small subpleural nodules are also seen in nearly 80% of patients. Parenchymal cysts are present in roughly two-thirds of all patients (Figures 15.1 and 15.2). Pleural effusions are rare.

Importance

Lymphocytic interstitial pneumonia in the adult is a benign disorder characterized by infiltration of the pulmonary interstitium by lymphocytes and plasma cells [1, 2]. LIP is characteristically steroid responsive.

Type
Chapter
Information
Pearls and Pitfalls in Thoracic Imaging
Variants and Other Difficult Diagnoses
, pp. 38 - 39
Publisher: Cambridge University Press
Print publication year: 2011

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References

Honda, OJohkoh, TIchikado, KDifferential diagnosis of lymphocytic interstitial pneumonia and malignant lymphoma on high-resolution CTAJR Am J Roentgenol 1999 173 71CrossRefGoogle ScholarPubMed
Johkoh, TMuller, NLPickford, HALymphocytic interstitial pneumonia: thin-section CT findings in 22 patientsRadiology 1999 212 567CrossRefGoogle ScholarPubMed

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