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6 - Application of Pharmacokinetics and Pharmacodynamics and Signal Analysis to Drug Administration in Anaesthesia

from Section 1 - Basic Principles

Published online by Cambridge University Press:  03 December 2019

Pedro L. Gambús
Affiliation:
Hospital Clinic de Barcelona, Spain
Jan F. A. Hendrickx
Affiliation:
Aalst General Hospital, Belgium
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Summary

In a recent review of the performance of closed-loop systems in anaesthesia, Brogi et al [2] defined a closed-loop system as an automated control system designed to maintain a given variable around a desired set point. The key components of these systems, sensors, controllers and actuators, are outlined in Table 6.1.

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Personalized Anaesthesia
Targeting Physiological Systems for Optimal Effect
, pp. 82 - 102
Publisher: Cambridge University Press
Print publication year: 2020

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