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8 - Overview of Basic Statistical Testing

Published online by Cambridge University Press:  05 June 2012

James N. Thompson, Jr
Affiliation:
University of Oklahoma
Jenna J. Hellack
Affiliation:
University of Oklahoma
Gerald Braver
Affiliation:
University of Oklahoma
David S. Durica
Affiliation:
University of Oklahoma
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Summary

In earlier chapters, such as Chapter 5, we discussed probability and statistics as they apply to a specific kind of genetic problem. Here we want to take a more general view of biostatistics and introduce some of the different ways one can describe relationships and test hypotheses.

The term statistics refers to the mathematical process of collecting, analyzing, interpreting, and presenting numerical data. Some statistical measures are purely descriptive, such as the sample mean or values of dispersal like the range, standard deviation, and variance. Other statistical measures are designed to evaluate relationships among groups of data or to test hypotheses about them.

Some descriptive statistics important in genetic analyses are discussed in more detail in Chapter 9, which focuses on quantitative genetic traits. Many quantitatively varying traits, such as seed number and tail length, approximate a normal distribution. The mean is the average value for a data set, and the variance is a measure of dispersal around the mean. The standard deviation is the square root of the variance and divides a normal distribution into subgroups of known size (for example, 68 percent of the data points fall within one standard deviation of the mean, 95 percent fall within two standard deviations, and 99 percent fall within three).

In describing relationships within and among the data points, it is useful to distinguish between two general types of statistical tests. Parametric statistic tests assume a normal distribution of the data; nonparametric statistics do not.

Type
Chapter
Information
Primer of Genetic Analysis
A Problems Approach
, pp. 84 - 86
Publisher: Cambridge University Press
Print publication year: 2007

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