Book contents
- Seminars in Clinical Psychopharmacology
- College Seminars Series
- Seminars in Clinical Psychopharmacology
- Copyright page
- Contents
- Contributors
- Foreword
- Preface
- Editor’s Note on Nomenclature
- Neuroscience-Based Nomenclature Glossary
- Abbreviations
- Part 1 Basic Science and General Principles
- Chapter 1 A Brief History of Psychopharmacology
- Chapter 2 Psychiatric Drug Discovery and Development
- Chapter 3 Neurotransmission and Mechanisms of Drug Action
- Chapter 4 Pharmacodynamics and Pharmacokinetics
- Chapter 5 Pharmacogenomics and Psychopharmacology
- Chapter 6 Good Clinical Practice in Psychopharmacology
- Part 2 Psychopharmacology of the Main Psychotropic Drug Groups
- Part 3 Specific Therapeutic Areas
- Index
- References
Chapter 3 - Neurotransmission and Mechanisms of Drug Action
from Part 1 - Basic Science and General Principles
Published online by Cambridge University Press: 29 May 2020
- Seminars in Clinical Psychopharmacology
- College Seminars Series
- Seminars in Clinical Psychopharmacology
- Copyright page
- Contents
- Contributors
- Foreword
- Preface
- Editor’s Note on Nomenclature
- Neuroscience-Based Nomenclature Glossary
- Abbreviations
- Part 1 Basic Science and General Principles
- Chapter 1 A Brief History of Psychopharmacology
- Chapter 2 Psychiatric Drug Discovery and Development
- Chapter 3 Neurotransmission and Mechanisms of Drug Action
- Chapter 4 Pharmacodynamics and Pharmacokinetics
- Chapter 5 Pharmacogenomics and Psychopharmacology
- Chapter 6 Good Clinical Practice in Psychopharmacology
- Part 2 Psychopharmacology of the Main Psychotropic Drug Groups
- Part 3 Specific Therapeutic Areas
- Index
- References
Summary
This chapter falls into three broad sections. The first considers basic principles and information regarding neurons, the nerve impulse and neurotransmission. The second section considers the principle neurotransmitters in the brain: acetylcholine, the catecholamines, dopamine, serotonin (5-hydroxytryptamine (5-HT)), histamine and the amino acid neurotransmitters. The final section reviews minor neurotransmitters, namely neuropeptides, purine neurotransmitters, prostaglandins, neurosteroids, gaseous transmitters and endocannabinoids. It is not possible for this chapter to provide a comprehensive and in-depth view of neurotransmission. This is a rapidly advancing field and those wishing to obtain a more extensive account should consult the numerous reviews and monographs. However, the main areas of the subject are covered, and this will provide a basis for the reader to appreciate the succeeding chapters of this book.
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- Seminars in Clinical Psychopharmacology , pp. 69 - 123Publisher: Cambridge University PressPrint publication year: 2020