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8 - New genes for old

from PART II - Engineering genes

Published online by Cambridge University Press:  16 March 2010

Susan Aldridge
Affiliation:
Clinical Sciences Centre, London
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Summary

Increasingly, medical research is dominated by DNA. The hunt is on for genes that can help to answer the really big questions, such as how does a single cell grow and develop into a complex body, and what really causes cells to grow into tumours sometimes. At the same time new DNA-based drugs and therapies are making their way from the research laboratory into the hospitals and general practitioners' surgeries.

Life, death and the cell

In California, there is a group of people who believe humans are meant to be immortal and that our bodies can last indefinitely if we only have the right psychological outlook! There is absolutely no scientific evidence for this, but the belief that the cells that make up our bodies are immortal was certainly once very widely accepted. Now our view of the life expectancy of cells has changed completely. According to the latest (and still controversial) research, the natural state of our cells is death, and only the constant prodding of genetic signals actually keeps them alive.

The myth of cell immortality originated with Nobel Prize winner Alexis Carrel, a French surgeon who was interested in organ transplantation and tissue culture. In 1912, he started to culture some cells from a chick's heart to see how long they would survive outside the animal's body. When they outgrew their culture vessel, they were divided up and transferred to new vessels – a process known as subculturing.

Type
Chapter
Information
The Thread of Life
The Story of Genes and Genetic Engineering
, pp. 165 - 180
Publisher: Cambridge University Press
Print publication year: 1996

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  • New genes for old
  • Susan Aldridge, Clinical Sciences Centre, London
  • Book: The Thread of Life
  • Online publication: 16 March 2010
  • Chapter DOI: https://doi.org/10.1017/CBO9780511661570.009
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  • New genes for old
  • Susan Aldridge, Clinical Sciences Centre, London
  • Book: The Thread of Life
  • Online publication: 16 March 2010
  • Chapter DOI: https://doi.org/10.1017/CBO9780511661570.009
Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

  • New genes for old
  • Susan Aldridge, Clinical Sciences Centre, London
  • Book: The Thread of Life
  • Online publication: 16 March 2010
  • Chapter DOI: https://doi.org/10.1017/CBO9780511661570.009
Available formats
×