This book addresses the molecular bases of some of the most important biochemical rhythms known at the cellular level. Clarifying the mechanism of these oscillatory phenomena is of key importance for understanding the origin as well as the physiological function of these rhythms, and the conditions in which simple periodic behaviour transforms into complex oscillations including bursting and chaos. It will appeal to graduate students and researchers in a wide variety of fields. On the one hand, it will be of interest to life scientists such as biochemists, cell biologists, medical scientists, pharmacologists and chronobiologists. On the other hand, scientists studying nonlinear phenomena, including oscillations and chaos, in chemistry, physics, mathematics and mathematical biology will also find these ideas of value.

‘The book beautifully illustrates the art of modelling … The author has been studying the theory of oscillations and rhythms for 25 years and brings a great deal of experience to bear on this book … It is an excellent read and will appeal to a wide-ranging audience, from students moving into the area to established researchers in the field, and from mathematical modellers to experimentalists in the life sciences.’

Source: Trends in Biochemical Sciences

‘… an extraordinarily impressive volume. I am fully confident that it will be the definitive work in this area for years to come.’

Paul Rapp - Professor of Physiology, Medical College of Pennsylvania

‘It really is a very impressive tome and is a superb addition to the literature. It is quite clearly going to be the reference book on oscillations.’

James D. Murray - Professor of Applied Mathematics and Mathematical Biology, University of Washington, Seattle