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  1. Home
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  3. Biochemistry and Physiology of the Neutrophil
  • Cited by 89
Publisher:
Cambridge University Press
Online publication date:
February 2010
Print publication year:
1994
Online ISBN:
9780511608421
DOI:
https://doi.org/10.1017/CBO9780511608421
Subjects:
Life Sciences, Microbiology and Immunology, Molecular Biology, Biochemistry, and Structural Biology
Information

Book description

This book describes the role of the neutrophil in infection and inflammation and provides an up-to-date review of the biochemistry and physiology of these cells, highlighting the mechanisms by which they seek out and destroy pathogenic micro-organisms. The development of these cells during haematopoiesis is described and the mechanisms which lead to the production of reactive oxidants and the intracellular signal transduction systems which lead to the cell's activation are reviewed. The book also discusses recent discoveries concerning the role of cytokines in the regulation of neutrophil function together with the importance of the neutrophil as a generator of inflammatory cytokines. Finally there is a description of the biochemical defects that give rise to some of the neutrophil-associated human diseases.

Reviews

"...a useful basic reference and I would recommend it to immunologists, microbiologists, biochemists, physiologists, infectious disease specialists, hematologists, or to anyone whose interest lies in immunology or microbiology." John O. Naim, Immunological Investigations

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