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Current techniques for studying biological macromolecules and their interactions are based on the application of physical methods, ranging from classical thermodynamics to more recently developed techniques for the detection and manipulation of single molecules. Reflecting the advances made in biophysics research over the past decade, and now including a new section on medical imaging, this new edition describes the physical methods used in modern biology. All key techniques are covered, including mass spectrometry, hydrodynamics, microscopy and imaging, diffraction and spectroscopy,…
Provides comprehensive coverage and up-to-date treatment of the full range of physical methods used in current biological research as well as in medical physics, illustrated using real-world examples
Each method includes a brief historical introduction, theoretical principles, applications, advantages and limitations, and concludes with a checklist of key ideas that summarize the important points for students
Includes all the necessary background to ensure accessibility for biologists, physicists, and those with medical backgrounds
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Authors
Nathan R. Zaccai,University of Cambridge
Nathan R. Zaccai is a Research Associate at the Cambridge Institute for Medical Research, University of Cambridge. His current research focuses on the molecular and thermodynamic basis of the transport and presentation at cell surfaces of proteins involved in pathogen evasion and host immunity.
Igor N. Serdyuk,Formerly of the Institute of Protein Research, Pushchino, Moscow Region
Joseph Zaccai is Directeur de Recherche Emeritus at the Centre Nationale de la Recherche Scientifique (CNRS), Paris and Visiting Scientist at the Institut Laue-Langevin, France and Institut de Biologie Structurale, Grenoble. His current research interests include the exploration of the role of dynamics and physical chemical limits for life. He has many years of experience in teaching biophysics to biologists, medical students, and physicists.
Joseph Zaccai,Institut Laue-Langevin
Igor N. Serdyuk (1939–2012) was Professor of Molecular Biology and Head of the Laboratory of Nucleoprotein Physics at the Institute of Protein Research, Russian Academy of Sciences, Moscow.