Hostname: page-component-78c5997874-fbnjt Total loading time: 0 Render date: 2024-11-07T13:03:52.608Z Has data issue: false hasContentIssue false
  • English
  • Français

Abnormal speech perception in schizophrenia with auditory hallucinations

Published online by Cambridge University Press:  24 June 2014

Seung-Hwan Lee ,
Young-Cho Chung ,
Jong-Chul Yang ,
Yong-Ku Kim  and
Kwang-Yoon Suh
Seung-Hwan Lee
Affiliation:
Department of Psychiatry, College of Medicine, Inje University
Young-Cho Chung
Affiliation:
Department of Psychiatry, College of Medicine, Chonnam University
Jong-Chul Yang
Affiliation:
Department of Psychiatry, College of Medicine, Chonnam University
Yong-Ku Kim*
Affiliation:
Department of Psychiatry, College of Medicine, Korea University, Seoul, Korea
Kwang-Yoon Suh
Affiliation:
Department of Psychiatry, College of Medicine, Korea University, Seoul, Korea
*
Yong-Ku Kim MD PhD, Department of Psychiatry, Ansan Hospital, Korea University Medical Centre, College of Medicine 516, Go-Jan Dong, Ansan City, Kyunggi Province, Korea, 425-020. Tel: 82-31-412-5140; Fax: 82-31-412-5144; E-mail: yongku@korea.ac.kr
Get access Rights & Permissions [Opens in a new window]

Abstract

Background:

The neurobiological mechanism of auditory hallucination (AH) in schizophrenia remains elusive, but AH can be caused by the abnormality in the speech perception system based on the speech perception neural network model.

Objectives:

The purpose of this study was to investigate whether schizophrenic patients with AH have the speech processing impairment as compared with schizophrenic patients without AH, and whether the speech perception ability could be improved after AH had subsided.

Methods:

Twenty-four schizophrenic patients with AH were compared with 25 schizophrenic patients without AH. Narrative speech perception was assessed using a masked speech tracking (MST) task with three levels of superimposed phonetic noise. Sentence repetition task (SRT) and auditory continuous performance task (CPT) were used to assess grammar-dependent verbal working memory and non-language attention, respectively. These tests were measured before and after treatment in both groups.

Results:

Before treatment, schizophrenic patients with AH showed significant impairments in MST compared with those without AH. There were no significant differences in SRT and CPT correct (CPT-C) rates between both groups, but CPT incorrect (CPT-I) rate showed a significant difference. The low-score CPI-I group showed a significant difference in MST performance between the two groups, while the high-score CPI-I group did not. After treatment (after AH subsided), the hallucinating schizophrenic patients still had significant impairment in MST performance compared with non-hallucinating schizophrenic patients.

Conclusions:

Our results support the claim that schizophrenic patients with AH are likely to have a disturbance of the speech perception system. Moreover, our data suggest that non-language attention might be a key factor influencing speech perception ability and that speech perception dysfunction might be a trait marker in schizophrenia with AH.

Keywords

attentionauditory hallucinationcognitionmemoryschizophreniaspeech perception
Type
Original Article
Information
Acta Neuropsychiatrica , Volume 16 , Issue 3 , June 2004 , pp. 154 - 159
Copyright
Copyright © 2004 Blackwell Munksgaard

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Bentall, RP. The illusion of reality: a review and integration of psychological research on hallucinations. Psychol Bull 1990;107: 82–95.CrossRefGoogle ScholarPubMed
Frith, C. The role of the prefrontal cortex in self-consciousness: the case of auditory hallucinations. Philos Trans R Soc Lond B Biol Sci 1996;351: 1505–1512.Google ScholarPubMed
McGuire, PK, Silbersweig, DA, Murray, RM, David, AS, Frackowiak, RS, Frith, CD. Functional anatomy of inner speech and auditory verbal imagery. Psychol Med 1996;26: 29–38.CrossRefGoogle ScholarPubMed
McGuire, PK, Shah, GM, Murray, RM. Increased blood flow in Broca's area during auditory hallucinations in schizophrenia. Lancet 1993;342: 703–706.CrossRefGoogle ScholarPubMed
Silbersweig, DA, Stern, E, Frith, Cet al. A functional neuroanatomy of hallucinations in schizophrenia. Nature 1995;378: 176–179.CrossRefGoogle ScholarPubMed
Suzuki, M, Yuasa, S, Minabe, Y, Murata, M, Kurachi, M. Left superior temporal blood flow increases in schizophrenic and schizophreniform patients with auditory hallucination: a longitudinal case study using 123I-IMP SPECT. Eur Arch Psychiatry Clin Neurosci 1993;242: 257–261.CrossRefGoogle Scholar
Hoffman, RE, Rapaport, J, Mazure, CM, Quinlan, DM. Selective speech perception alterations in schizophrenic patients reporting hallucinated ‘voices’. Am J Psychiatry 1999;156: 393–399.CrossRefGoogle ScholarPubMed
First, M, Spitzer, RL, Gibbon, M, William, JB. Structured Clinical Interview for DSM-IV Axis I Disorder – Patient Edition (SCID-I/P, Version 2.0). New York: Biometrics Research Department, New York State Psychiatric Institute, 1998. Google Scholar
Andreasen, NC. Scale for the Assessment of Positive Symptoms. Iowa City, Iowa :Department of Psychiatry College of Medicine, The University of Iowa, 1984. Google Scholar
Andreasen, NC. Scale for the Assessment of Negative Symptoms. Iowa City, Iowa :Department of Psychiatry College of Medicine, The University of Iowa, 1984. Google Scholar
Mirsky, AF, Lochhead, SJ, Jones, BP, Kugelmass, S, Walsh, D, Kendler, KS. On familial factors in the attentional deficit in schizophrenia: a review and report of two new subject samples. J Psychiatr Res 1992;26: 383–403.CrossRefGoogle ScholarPubMed
Benton, AL, Hamsher, K. Multilingual Aphasia Examination. Iowa City: University of Iowa, 1978. Google Scholar
American Psychiatric Association. Practice guideline for the treatment of patients with schizophrenia. Am J Psychiatry 1997;154: 1–63. CrossRefGoogle Scholar
Carter, C, Robertson, L, Nordahl, T, Chaderjian, M, Kraft, L, O'Shora-Celaya, L. Spatial working memory deficits and their relationship to negative symptoms in unmedicated schizophrenia patients. Biol Psychiatry 1996;40: 930–932.CrossRefGoogle ScholarPubMed
Leudar, I, Thomas, P, Johnston, M. Self-repair in dialogues of schizophrenics: effects of hallucinations and negative symptoms. Brain Lang 1992;43: 487–511.CrossRefGoogle ScholarPubMed
Addington, J, Addington, D, Maticka-Tyndale, E. Cognitive functioning and positive and negative symptoms in schizophrenia. Schizophr Res 1991;5: 123–134.CrossRefGoogle ScholarPubMed
Goldberg, TE, Gold, JM, Greenberg, Ret al. Contrasts between patients with affective disorders and patients with schizophrenia on a neuropsychological test battery. Am J Psychiatry 1993;150: 1355–1362.Google ScholarPubMed
Strauss, ME. Relations of symptoms to cognitive deficits in schizophrenia. Schizophr Bull 1993;19: 215–231.CrossRefGoogle ScholarPubMed
Earle-Boyer, EA, Serper, MR, Davidson, M, Harvey, PD. Continuous performance tests in schizophrenic patients. stimulus and medication effects on performance. Psychiatry Res 1991;37: 47–56.CrossRefGoogle ScholarPubMed
Serper, MR, Bergman, RL, Harvey, PD. Medication may be required for the development of automatic information processing in schizophrenia. Psychiatry Res 1990;32: 281–288.CrossRefGoogle ScholarPubMed
Spohn, HE, Strauss, ME. Relation of neuroleptic and anticholinergic medication to cognitive functions in schizophrenia. J Abnorm Psychol 1989;98: 367–380.CrossRefGoogle ScholarPubMed
Finkelstein, JR, Cannon, TD, Gur, RE, Gur, RC, Moberg, P. Attentional dysfunctions in neuroleptic-naive and neuroleptic-withdrawn schizophrenic patients and their siblings. J Abnorm Psychol 1997;106: 203–212.CrossRefGoogle ScholarPubMed
Servan-Schreiber, D, Cohen, JD, Steingard, S. Schizophrenic deficits in the processing of context. A test of a theoretical model. Arch Gen Psychiatry 1996;53: 1105–1112.CrossRefGoogle ScholarPubMed
Gilbertson, MW, Van Kammen, DP. Recent and remote memory dissociation: medication effects and hippocampal function in schizophrenia. Biol Psychiatry 1997;42: 585–595.CrossRefGoogle ScholarPubMed