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Dimensional models and neurobiology of personality disorders

Published online by Cambridge University Press:  18 September 2015

W. van den Brink
W. van den Brink*
Affiliation:
Academisch Medisch Centrum, Universiteit van Amsterdam, divisie Psychiatric Amsterdam Institute for Addiction Research
*
AMC divisie Psychiatrie, Tafelbergweg 25, 1105 BC Amsterdam
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Summary

Since the introduction of a separate axis in DSM-III (1980), the validity of the categorical nature of the classification of personality disorders has been seriously questioned. Subsequently, a number of multidimensional alternatives have been proposed based on statistical procedures or theoretical considerations. At the same time, the study of the neurobiological underpinnings of personality and personality disorders has created a better understanding of etiological and pathogenetic processes responsible for these chronic disorders. The findings of these studies corroborate some of the major findings of statistical studies regarding the nature of the frequent comorbidity of axis II disorders. In the discussion, a mixed, two-tier diagnostic model is proposed to serve both scientific and clinical aims without the disadvantages of an exclusive choice for either categorical or dimensional approaches to the classification of personality pathology.

Keywords

Personality disorderclassificationtaxonomyneurobiologyPersoonlijkheidsstoornisclassificatietaxonomieneurobiologie
Type
Research Article
Information
Acta Neuropsychiatrica , Volume 11 , Issue 1 , March 1999 , pp. 1 - 4
Copyright
Copyright © Scandinavian College of Neuropsychopharmacology 1999

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