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Le Sulphate de Vincristine dans le Traitement de la Leucose Aiguë de l'Enfance

Published online by Cambridge University Press:  01 August 2014

A. Colarizi
Affiliation:
Istituto di Clinica Pediatrica dell'Università di Roma
G. Stegagno
Affiliation:
Istituto di Clinica Pediatrica dell'Università di Roma
G. Digilio
Affiliation:
Istituto di Clinica Pediatrica dell'Università di Roma
G. Multari
Affiliation:
Istituto di Clinica Pediatrica dell'Università di Roma

Summary

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41 children with acute leukemia were treated with Vincristine Sulphate. Total remission was obtained in 17 out of 22 patients (77%) in whom Vincristine was used as the first drug.

19 patients who had been treated previously with other antimitotic drugs and have become resistant to them, received Vincristine: total remission occurred in 7 cases and partial remission in 3 cases within 4-10 weeks of therapy.

A case is reported of a child still surviving three years and seven months from the beginning of the disease and two years and 4 months from completion of therapy with Vincristine.

Type
Research Article
Copyright
Copyright © The International Society for Twin Studies 1967

References

Bibliographie

Freireich, E. J., Frei, E. (1964). Recent advances in acute leukemia. II. In: Progress in Hematology, IV. Grune, & Stratton, Eds., New York.Google Scholar
Freireich, E. J. et al. (1964). Quadruple combination therapy (VAMP) for acute lymphocytic leukemia of childhood. Proc. Amer. Ass. Cancer. Res., 5: 20.Google Scholar
Freireich, E. J. et al., (1965). Combination chemotherapy of acute leukemia. Proc. XI Internat. Congr. Pediat., Tokyo.Google Scholar
Karon, M. R. et al. (1962). A preliminary report on vincristine-sulfate. A new active agent for the treatment of acute leukemia. Pediatrics, 30: 791.Google Scholar
Stegagno, G. et al. (1964 a). Trattamento della leucemia acuta del bambino. (Primi risultati con il Vincri-stin). La Settimana degli Ospedali, 6: 435.Google Scholar
Stegagno, G. et al. (1964). Primi risultati del trattamento della leucemia acuta del bambino con la Vincristina. Atti XXX Congr. Ital. Pediat., Catania.Google Scholar
Zuelzer, W. W. (1964)). Implications of longterm survival in acute “ stemcells ” leukemia of childhood treated with composite cyclic therapy. Blood, 24: 477.Google Scholar