Hostname: page-component-7bb8b95d7b-l4ctd Total loading time: 0 Render date: 2024-09-15T15:20:19.627Z Has data issue: false hasContentIssue false
  • English
  • Français

The accumulation of copper in the liver of lambs on diets containing dried poultry waste

Published online by Cambridge University Press:  02 September 2010

N. F. Suttle ,
C. S. Munro  and
A. C. Field
N. F. Suttle
Affiliation:
Moredun Research Institute, Edinburgh EH 17 7JH
C. S. Munro
Affiliation:
Moredun Research Institute, Edinburgh EH 17 7JH
A. C. Field
Affiliation:
Moredun Research Institute, Edinburgh EH 17 7JH
Get access

Abstract

(1) Eight groups of newly weaned lambs were given diets containing 15, 30, 45 or 60% dried poultry waste (DPW) from battery or broiler units in a 4x2 factorial experiment lasting 16 weeks. The Cu content of the diets increased from 12·7 to 35·5 and from 16·1 to 47·1 mg/kg DM with increasing levels of battery and broiler waste, respectively.

(2) As inclusion rates increased, final liver Cu concentrations were 269, 318, 379 and 441 with battery waste and 686, 1009, 877 and 874 mg/kg DM with broiler waste. Total liver Cu accumulation, though higher on broiler than on battery waste, was not proportional to inclusion rate and reached a plateau at the 30% level for both sources.

(3) Mean hepatic Cu retention was constant at 4·8 % of Cu intake with battery waste but decreased from 8·3 to 3·2% as level of broiler waste increased.

(4) Plasma asparate amino transferase (PAAT) levels were highest in groups given broiler waste and final PAAT concentrations were correlated with liver Cu concentration, reaching levels associated with Cu toxicosis in some individuals. The effect of DPW on PAAT was not proportional to inclusion rate.

(5) The factors responsible for the observed variations in liver Cu accumulation between sources and inclusion rates and the possibility of Cu toxicity occurring in sheep given DPW are discussed.

Type
Research Article
Information
Animal Production , Volume 26 , Issue 1 , February 1978 , pp. 39 - 45
Copyright
Copyright © British Society of Animal Science 1978

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

Abdellatif, A. M. M. 1968. Conditioned hypocuprosis: some effects of diet on copper storage in ruminants. Versl. Landbouwk. Onderz. No. 709.Google Scholar
Blair, R. 1974. Evaluation of dehydrated poultry waste as a feed ingredient for poultry. Fedn. Proc. Fedn Am. Socs exp. Biol. 33: 1934–36.Google ScholarPubMed
Bremner, I., Mills, C. F. and Young, B. W. 1976. Protective effects of zinc supplementation against copper toxicosis in sheep. Br. J. Nutr. 35: 551–561.CrossRefGoogle Scholar
Field, A. C., Munro, C. S. and Suttle, N. F. 1977. Dried poultry manure as a source of phosphorus for sheep. J. agric. Sci., Camb. In press.CrossRefGoogle Scholar
Fontenot, J. P., Webb, K. E., Buehler, R. J., Harmon, B. W. and Phillips, W. A. 1972. Effects of feeding different levels of broiler litter to ewes for long periods of time on performance and health. Va Poly. Inst. State Univ. Res. Div. Rep., No. 145, pp. 33–39.Google Scholar
Hill, R. and Williams, H. Li. 1965. The effects on intensively reared lambs of diets containing excess copper. Vet. Rec. 77: 1043–1045.CrossRefGoogle ScholarPubMed
Jensen, L. S. 1977. Evaluation of copper as a feed additive for poultry. Proc. 1977 Georgia Nutrition Conf., pp. 54–64. University of Georgia.Google Scholar
Karmen, A., Wróblewski, F. and Ladue, J. S. 1955. Transaminase activity in human blood. J. din. Invest. 34: 126–133.Google ScholarPubMed
MacPherson, A. and Hemingway, R. G. 1965. Effects of protein intake on the storage of copper in the liver of sheep. J. Sci. Fd Agric. 16: 220–227.CrossRefGoogle Scholar
MacPherson, A. and Hemingway, R. G. 1969. The relative merits of various blood analyses and liver function tests in giving an early diagnosis of chronic copper poisoning in sheep. Br. vet. J. 125: 213–221.CrossRefGoogle Scholar
Smith, L. W. 1974. Dehydrated poultry excreta as a crude protein supplement for ruminants. Wld Anim. Rev., No. 11, pp. 6–11.Google Scholar
Suttle, N. F. 1974. A technique for measuring the biological availability of copper to sheep, using hypocupraemic ewes. Br. J. Nutr. 32: 395–405.CrossRefGoogle ScholarPubMed
Suttle, N. F. 1977. Reducing the potential toxicity of concentrates to sheep by the use of molybdenum and sulphur supplements. Anim. Feed Sci. Technol. 2: 225–266.CrossRefGoogle Scholar
Suttle, N. F. and Field, A. C. 1970. Effects of dietary calcium and phosphorus concentrations on the faecal excretion of copper, manganese and zinc in sheep. Proc. Nutr. Soc. 29: 33A–34A.Google Scholar
Suttle, N. F. and McLauchlan, M. 1976. Predicting the effects of dietary molybdenum and sulphur on the availability of copper to ruminants. Proc. Nutr. Soc. 35: 22A–23A.Google ScholarPubMed
Suttle, N. F. and Price, J. 1976. The potential toxicity of copper-rich animal excreta to sheep. Anim. Prod. 23: 233–241.Google Scholar
Thompson, R. H. and Blanchflower, W. J. 1971. Wet-ashing apparatus to prepare biological materials for atomic absorption spectrophotometry. Lab. Pract. 20: 859–861.Google ScholarPubMed
Todd, J. R. 1969. Chronic copper toxicity of ruminants. Proc. Nutr. Soc. 28: 189–198.CrossRefGoogle ScholarPubMed