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Growth-related hormones in plasma of bulls, steers and heifers given food with two different energy levels

Published online by Cambridge University Press:  02 September 2010

R. Röpke ,
D. Schams ,
F. J. Schwarz  and
M. Kirchgessner
R. Röpke
Affiliation:
Institute of Physiology, Weihenstephan Research Centre for Milk and Food, Technical University of Munich, 85350 Freising, Vöttingerstrasse 45, Germany
D. Schams
Affiliation:
Institute of Physiology, Weihenstephan Research Centre for Milk and Food, Technical University of Munich, 85350 Freising, Vöttingerstrasse 45, Germany
F. J. Schwarz
Affiliation:
Institute of Nutrition Physiology, Technical University Munich, Freising-Weihenstephan, 85350 Freising, Germany
M. Kirchgessner
Affiliation:
Institute of Nutrition Physiology, Technical University Munich, Freising-Weihenstephan, 85350 Freising, Germany
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Abstract

Concentrations of growth hormone (GH), insulin-like growth factor (IGF-1), insulin and glucagon were determined in the plasma of growing bulls, steers and heifers (no. = 138 in total, German Simmental breed). The animals were offered either a high level or a low level of energy resulting in relatively high and low average daily gain. Trials were subdivided into two experimental series and started at approximately 3 months of age at an average live weight of 110 kg. The animals were slaughtered at different body weights from 200 to 510 kg (heifers) or 660 kg (bulls, steers). Blood samples (needle puncture) were collected at biweekly intervals. Frequent samples time-course analysis of GH were taken by catheter from nine animals in total. Concentrations of GH declined during growth in steers and heifers as well as in bulls in blood samples collected by means of a catheter. IGF-1 and insulin concentrations increased from the start of the trial onwards up to different ages among the groups. Concentrations of glucagon constantly decreased from the start of the trial until slaughter. Significant differences (P < 0·05) in concentrations ofGH, IGF-1 and insulin could be observed between sexes and levels of nutrition, with the highest GH and IGF-1 levels in bulls followed by steers and heifers. In contrast insulin values were highest in heifers followed by steers and bulls. A high level of nutrition increased concentrations of IGF-1 and insulin in all sexes.

Keywords

cattleintakegrowth hormoneIGF-1insulin
Type
Research Article
Information
Animal Production , Volume 59 , Issue 3 , December 1994 , pp. 367 - 377
Copyright
Copyright © British Society of Animal Science 1994

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References

Alexandrides, T., Moses, A. and Smith, R. J. 1989. Developmental expression of receptors for insulin, insulin-like growth factor I (IGF-I), and IGF-II in rat skeletal muscle. Endocrinology 124: 1064–1076.CrossRefGoogle ScholarPubMed
Anfinson, M. S., Davis, S. L., Christian, E. and Everson, D. O. 1975. Episodic secretion of growth hormone in steers and bulls: an analysis of frequency and magnitude of secretory spikes occurring in a 14 hour period. Proceedings of Western Section of American Society for Animal Science 26: 175–177.Google Scholar
Augustini, C., Branscheid, W., Schwarz, F. J. and Kirchgessner, M. 1993. [Growth specific alterations of carcass quality of fattening cattle of German Simmentals. 4. Influence of feeding intensity and slaughter weight on the coarse tissue composition of steer carcass]. Fleisclwirtschaft 73: 1058–1065.Google Scholar
Ballard, F. J., Read, L. C., Francis, G. L., Bagley, C. J. and Wallace, J. C. 1986. Binding properties and biological potencies of insulin-like growth factors in L6 myoblasts. Biochemical Journal 233: 223–230.CrossRefGoogle ScholarPubMed
Baxter, R. C., Bryson, J. M. and Turtle, J. R. 1980. Somatogenic receptors of rat liver: regulation by insulin. Endocrinology 107: 1176–1181.CrossRefGoogle ScholarPubMed
Beeby, J. M., Haresign, W. and Swan, H. 1988. Endogenous hormone and metabolite concentrations in different breeds of beef steer on two systems of production. Animal Production 47: 231–244.Google Scholar
Berelowitz, M., Szabo, M., Frohman, L. A., Firestone, S., Chu, L. and Hintz, R. L. 1981. Somatomedin-C mediates growth hormone negative feedback by effects on both the hypothalamus and the pituitary. Science, New York 212: 1279–1281.CrossRefGoogle ScholarPubMed
Breier, B. H., Bass, J. J., Butler, J. H. and Gluckman, P. D. 1986. The somatotrophic axis in young steers: influence of nutritional status on pulsatile release of growth hormone and circulating concentrations of insulin-like growth factor 1. journal of Endocrinology 111: 209–215.CrossRefGoogle ScholarPubMed
Breier, B. H., Gluckman, P. D. and Bass, J. J. 1988. Influence of nutritional status and oestradiol-17β on plasma growth hormone, insulin-like growth factors-I and II and the response to exogenous growth hormone in young steers. Journal of Endocrinology 118: 243–250.CrossRefGoogle ScholarPubMed
Brockman, R. P. and Bergman, E. N. 1975. Effect of glucagon on plasma alanine and glutamine metabolism and hepatic gluconeogenesis in sheep. American journal of Physiology 228: 1627–1633.CrossRefGoogle ScholarPubMed
Brockman, R. P., Bergman, E. N., Joo, P. K. and Manns, J. G. 1975. Effects of glucagon and insulin on. net hepatic metabolism of glucose precursors in sheep. American journal of Physiology 239: 3344–3350.Google Scholar
Buttery, P. J. 1983. Hormonal control of protein deposition in animals. Proceedings of the Nutrition Society 42: 137–148.CrossRefGoogle ScholarPubMed
Chikhou, F., Moloney, A. P., Enright, W. J., Austin, F. H. and Roche, J. F. 1989. Acute and chronic effects of administration of cimaterol to Friesian steers on blood hormones and metabolites. Fortieth annual meeting of the European Association for Animal Production, Dublin, pp. 413–420.Google Scholar
Dejong, A. 1982. Patterns of plasma concentrations of insulin and glucagon after intravascular and intraruminal administration of volatile fatty acids in the goat. journal of Endocrinology 92: 357–370.CrossRefGoogle Scholar
Della-Fera, M. A., Buonomo, F. C. and Baile, C. A. 1986. Growth hormone secretory responsiveness to multiple injections of growth hormone-releasing factor in sheep. Domestic Animal Endocrinology 3: 153–164.CrossRefGoogle Scholar
Douglas, R. G., Gluckman, P. D., Ball, K., Breier, B. H. and Shaw, J. H. F. 1991. The effects of infusion of insulin-like growth factor (IGF-1), IGF-II, and insulin on glucose and protein metabolism in fasted lambs. journal of Clinical Investigations 88: 614–622.CrossRefGoogle ScholarPubMed
Dubreuil, P., Pelletier, G., Petitclerc, D., Lapierre, H., Couture, Y., Brazeau, P., Gaudreau, P. and Morisset, J. 1987. Influence of age and sex on basal secretion of growth hormone (GH) and GH-induced release by porcine GH-releasing factor pGRF(l-29NH2) in growing pigs. Domestic Animal Endocrinology 4: 299–307.CrossRefGoogle Scholar
Fiems, L. O., Decuypere, E. and Boucque, Ch. V. 1989. A note on the effect of feeding cimaterol on some endocrinological parameters and growth in different types of finishing beef bulls. Animal Production 48: 601–605.CrossRefGoogle Scholar
Gluckman, P. D., Breier, B. H. and Davis, S. R. 1987. Physiology of the somatotropic axis with particular reference to the ruminant. journal Animal Science 70: 442–466.Google Scholar
Granger, A. L., Wyatt, W. E., Craig, W. M., Thompson, D. L. and Hembry, F. G. 1989. Effects of breed and wintering diet on growth, puberty and plasma concentrations of growth hormone and insulin-like growth factor 1 in heifers. Domestic Animal Endocrinology 6: 253–263.CrossRefGoogle ScholarPubMed
Gregory, N. G., Truscott, T. G. and Wood, J. D. 1982. Insulin secretion in relation to fatness in cattle. journal of Science of Food Agriculture 33: 276–282.CrossRefGoogle ScholarPubMed
Hammond, A. C., Elsasser, T. H., Kunkle, W. E., Rumsey, T. S., Williams, M. J. and Butts, W. T. 1990. Effects of winter nutrition and summer pasture or feedlot diet on plasma insulin-like growth factor I (IGF-I) and the relationship between circulating concentrations of IGF-I and thyroid hormones in steers. Domestic Animal Endocrinology 7: 465–475.CrossRefGoogle ScholarPubMed
Hannon, K., Gronowski, A. and Trenkle, A. 1991. Relationship of liver and skeletal muscle IGF-1 mRNA to plasma GH profile, production of IGF-1 by liver, plasma IGF-1 concentrations and growth rates of cattle. Proceedings of the Society for Experimental Biology and Medicine 196: 155–163.CrossRefGoogle ScholarPubMed
Harper, J. M. M., Soar, J. B. and Buttery, P. J. 1987. Changes in protein metabolism of ovine primary muscle cultures on treatment with growth hormone, insulin, insulin-like growth factor I or epidermal growth factor. journal of Endocrinology 112: 87–96.CrossRefGoogle ScholarPubMed
Hart, I. C. and Johnsson, I. D. 1986. Growth hormone and growth in meat producing animals. In Control and manipulation of animal growth (ed. Buttery, P. J., Lindsay, D. B. and Haynes, N. B.), pp. 135–139. Butterworths, London.CrossRefGoogle Scholar
Kirchgessner, M., Schwarz, F., Otto, R., Reimann, W. and Heindle, U. 1993. [Energy and nutrient contents of carcass and empty body of growing bulls, heifers and steers (German Simmental) fed with two different energy levels]. Journal of Animal Physiology and Animal Nutrition 70: 266–277.CrossRefGoogle Scholar
Louveau, I. and Etherton, T. D. 1992. Characterization of somatotropin binding sites in pig skeletal muscle. journal of Animal Science 70: 1801–1805.CrossRefGoogle ScholarPubMed
Merriam, G. R. and Wachter, K. W. 1982. Algorithms for the study of episodic hormone secretion. American Journal of Physiology 243: E310–E318.Google Scholar
Mersman, H. J. 1987. Nutritional and endocrinological influences on the composition of animal growth. Progress in Food and Nutrition Science 11: 175–201.Google Scholar
Ostaszewski, P., Nissen, S. and Trenkle, A. 1990. Changes in insulin, glucagon and growth hormone secretion rates in sheep fed supplemental energy. journal of Animal Physiology and Animal Nutrition 63: 103–108.CrossRefGoogle Scholar
Plouzek, C. A. and Trenkle, A. 1991. Insulin-like growth factor-I concentrations in plasma of intact and castrated male and female cattle at four ages. Domestic Animal Endocrinology 8: 73–79.CrossRefGoogle ScholarPubMed
Ronge, H. and Blum, J. W. 1989. Insulin-like growth factorI during growth in bulls. Reproduction Nutrition Developpement 29: 105–111.CrossRefGoogle Scholar
Sauerwein, H., Meyer, H. H. D. and Schams, D. 1993. Divergent effects of estrogenes on the somatotropic axis in male and female calves. journal of Reproduction and Development 38: 271–278.CrossRefGoogle Scholar
Schams, D., Graf, F., Meyer, J., Graule, B., Mauthner, M. and Wollny, C. 1991. Changes in hormones, metabolites, and milk after treatment with sometribove (recombinant methionyl bST) in Deutsches Fleckvieh and German Black and White cows. journal of Animal Science 69: 1583–1592.CrossRefGoogle ScholarPubMed
Schams, D., Winkler, U., Schallenberger, E. and Karg, H. 1988. [Blood levels of growth hormone and insulin-like growth factor I from birth until puberty]. Deutsche Tierarztliche Wochenzeitschrift 95: 360–362.Google Scholar
Schwarz, F. J., Kirchgessner, M., Augustini, C. and Branscheid, W. 1992. [Growth specific alterations of carcass quality of fattening cattle of German Simmentals. 1. Growth rate of bulls, steers and heifers fed with different feeding intensity]. Fleischwirtschaft 72: 1584–1589.Google Scholar
Schwarz, F. J., Schams, D., Ropke, R., Kirchgessner, M., Kögel, J. and Matzke, P. 1993. Effects of somatotropin treatment on growth performance, carcass traits, and the endocrine system in finishing beef heifers. Journal of Animal Science 71: 2721–2731.CrossRefGoogle ScholarPubMed
Statistical Analysis Systems Institute. 1987. SAS user's guide. Statistical Analyses Systems Institute Inc., Cary, NC.Google Scholar
Verde, L. S. and Trenkle, A. 1987. Concentrations of hormones on plasma from cattle with different growth potentials. journal of Animal Science 64: 426–432.CrossRefGoogle ScholarPubMed