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The incidence of halothane sensitivity in British pigs

Published online by Cambridge University Press:  02 September 2010

A. J. Webb
A. J. Webb
Affiliation:
ARC Animal Breeding Research Organisation, West Mains Road, Edinburgh EH9 3JQ
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Abstract

An adverse reaction in pigs to the anaesthetic halothane at approximately 8 weeks of age appears to be controlled by a single recessive gene affecting stress susceptibility, lean content and reproductive performance. In a survey of British nucleus herds, a total of 2998 pigs between 5 weeks of age and 28 kg live weight were given 3-min halothane tests during visits to 17 breeders or companies. There were no positive halothane reactions among 764 Large Whites from 7 herds. The frequency of positive reaction among 1538 Landrace from 14 herds averaged 11%, with a range from 0 to 23 % in individual herds. Frequencies in other pure breeds or synthetic lines varied from 0 to 88%. British and foreign breeds are compared, and the possibility of eliminating the halothane gene is discussed.

Type
Research Article
Information
Animal Production , Volume 31 , Issue 1 , August 1980 , pp. 101 - 105
Copyright
Copyright © British Society of Animal Science 1980

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References

REFERENCES

Andren, H. and Persson, J. 1977. [The halothane test—a possible method for reducing stress susceptibility in pigs.] Svinskotsel 67: 22–23.Google Scholar
Andresen, E. and Jensen, P. 1977. Close linkage established between the HAL locus for halothane sensitivity and the PHI (phosphohexose isomerase) locus in pigs of the Danish Landrace breed. Nord. VetMed. 29: 502–504.Google Scholar
Ball, R. A., Topel, D. G., Annis, C. L. and Christian, L. L. 1973. Diagnostic aspects of Porcine Stress Syndrome. Proc. 76th A. Mtg U.S. Animal Health Ass., Miami Beach, pp. 517–530.Google Scholar
Bulla, J., Eikelenboom, G., Zelnik, J. and Poltarsky, J. 1979. Halothane test in early diagnosis of stress susceptibility. Acta Agric. scand., Suppl. 21, pp. 469–478.Google Scholar
Eikelenboom, G. 1979. The application of the halothane test in Dutch swine breeding and selection. Acta Agric. scand., Suppl. 21, pp. 413–417.Google Scholar
Eikelenboom, G., Minkema, D. and Van Eldik, P. 1976. The application of the halothane test: differences in production characteristics between pigs qualified as reactors (MHS-susceptible) and nonreactors. Proc. 3rd int. Conf. Production Disease in Farm Animals, Wageningen, pp. 183–187. Pudoc, Wageningen.Google Scholar
Eikelenboom, G., Minkema, D., Van Eldik, P. and Sybesma, W. 1979. Production traits of Dutch Landrace pigs as related to their genotype and phenotype for the halothane-induced Malignant Hyperthermia Syndrome. Proc. 30th A. Mtg Eur. Ass. Anim. Prod., Harrogate, Paper MP2.3.Google Scholar
Froystein, T., Schie, K. A. and Nøstvold, S. O. 1979. Halothane sensitivity, blood CPK-values and meat quality characteristics in pigs selected for rate of gain and backfat thickness. Acta Agric. scand., Suppl. 21, pp. 432–440.Google Scholar
Jensen, P. 1979. Incidence of halothane susceptibility in the Danish Landrace breed and its association with meat quality: preliminary report. Acta Agric. scand., Suppl. 21, pp. 427–431.Google Scholar
Jørgensen, P. F. 1979. Polymorphic systems in blood: associations with porcine halothane sensitivity and meat quality. Acta Agric. scand., Suppl. 21, pp. 386 395.Google Scholar
Lampo, P. 1978. Quantification of the halothane-anaesthesia-test for stress-susceptibility diagnosis in pigs. Proc. 5th Wld Congress int. Pig. Vet. Soc, Zagreb. Paper KA 28. Zrinski, Cakovec, Yugoslavia.Google Scholar
McGloughlin Patricia Ahern, C. P. and McLoughlin, J. V. 1979. Halothane sensitivity and pH, testing in Irish pigs. Acta Agric. scand., Suppl. 21, pp. 451–456.Google Scholar
McPhee, C. P., Takken, A. and D'arcy, K. J. 1979. Genetic variation in meat quality and the incidence of malignant hyperthermia syndrome in Large White and Landrace boars. Aust. J. exp. Agric. Anim. Husb. 19: 43–47.CrossRefGoogle Scholar
Meat and Livestock Commission. 1979. Pig Improvement Scheme Yearbook 1978 to 1979. Meat and Livestock Commission, Bletchley, Milton Keynes.Google Scholar
Minkema, D., Eikelenboom, G. and Van Eldik, P. 1976. Inheritance of M.H.S.-susceptibility in pigs. Proc. 3rd int. Conf. Production Disease in Farm Animals, Wageningen, pp. 203–207. Pudoc, Wageningen.Google Scholar
Ollivier, L., Sellier, P. and Monin, G. 1976. Frequency of the malignant hyperthermia syndrome (MHS) in some French pig populations: preliminary results. Proc. 3rd int. Conf. Production Disease in Farm Animals, Wageningen, pp. 208–210. Pudoc, Wageningen.Google Scholar
Schwörer, D. and Blum, J. 1979. [The halothane test for selection in pigs.] Der Kleinviehziichter 27: 237–242.Google Scholar
Smith, C. and Bampton, P. 1977. Inheritance of reaction to halothane anaesthesia in pigs. Genet. Res. 29: 287–292.CrossRefGoogle ScholarPubMed
Sybesma, W. and Eikelenboom, G. 1969. Malignant hyperthermia syndrome in pigs. Neth. J. Vet. Sci. 2: 155–160.Google Scholar
Wagner, E. and Pasterling, A. 1977. [Meat quality and stress susceptibility in pure- and crossbred pigs.] Proc. der Deutschen Gesellschaft für Ziichtungskunde. Univ. Bonn. (Mimeograph).Google Scholar
Webb, A. J. and Jordan, C. H. C. 1978. Halothane sensitivity as a field test for stress-susceptibility in the pig. Anim. Prod. 26: 157–168.Google Scholar