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Bioenergetics, bioengineering and growth

Published online by Cambridge University Press:  02 September 2010

A. J. F. Webster
Affiliation:
Department of Animal Husbandry, University of Bristol, Langford House, Langford, Bristol BS18 7DU
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Abstract

The effects of conventional and novel methods for the manipulation of growth in meat animals are reviewed within the context of the fundamental laws that determine the biological efficiency of energy conversion. Interspecies comparisons reveal large differences in the energetic efficiency of growth between mammals and birds. The similarity between mammals of different sizes is remarkable, both between and within species, which suggests that manipulation of growth rate per se has little effect on efficiency. The best way to improve the efficiency of growth is to maximize the conversion of metabolizable energy (ME) to lean tissue at all stages of maturation. The principal destination of ME is heat, however thermogenesis linked to essential metabolic functions is resistant to manipulation. It is more profitable to manipulate the partition of retained energy between protein and fat. Whether this is achieved by nutrition, conventional breeding or bioengineering, it is necessary to ensure that it does not compromise the normal health and vigour of the growing animal.

Type
Invited paper
Copyright
Copyright © British Society of Animal Science 1989

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References

REFERENCES

Agricultural Development and Advisoty Service. 1976. Nutrient allowances and composition of feedingstuffs for ruminants. Booklet 2987. Ministry of Agriculture, Fisheries and Food, London.Google Scholar
Agricultural Research Council. 1980. The Nutrient Requirements of Ruminant Livestock. Commonwealth Agricultural Bureaux, Slough.Google Scholar
Blaxter, K. L. 1962. The Energy Metabolism of Ruminants. Hutchinson, London.Google Scholar
Blem, C. R. 1978. The energetics of young Japanese quail (Coturnix coturnix japonica). Comparative Biochemistry and Physiology 59A: 219223.CrossRefGoogle Scholar
Brody, S. 1945. Bioenergetics and Growth: with Special Reference to the Efficiency Complex in Domestic Animals. Reinhold, New York.Google Scholar
Burrin, I. G., Ferrell, C. L. and Britton, R. A. 1988. Effect of feed intake of lambs on visceral organ growth and metabolism. Proceedings of 11th Symposium on Energy Metabolism of Farm Animals. EAAP Publication. In press.Google Scholar
Butterfield, R. M., Griffiths, D. A., Thompson, J. M., Zamora, J. and James, A. M. 1983. Changes in body composition relative to weight and maturity in large and small strains of Merino rams. Animal Production 36: 2937.Google Scholar
Buttery, P. J., Lindsay, D. B. and Haynes, N. B. 1986. Control and Manipulation of Animal Growth. Butterworths, London.Google Scholar
Campbell, R. G., Steele, N. C., Caperna, T. J., McMurtry, J. P. and Solomon, M. B. 1988. Effects of sex and exogenous porcine growth hormone administration on protein and lipid metabolism of growing pigs. Proceedings of 11th Symposium on Energy Metabolism of Farm Animals. EAAP Publication 43: 99102.Google Scholar
Coulson, R. A. and Herbert, J. D. 1981. Relationship between metabolic rate and various physiological and biochemical parameters. A comparison of alligator, man and shrew. Comparative Biochemistry and Physiology 69: 113.CrossRefGoogle Scholar
Eison, E. J., Barker, H. and Nagai, J. 1977. Body composition and energetic efficiency in two lines of mice selected for rapid growth rate and their F, crosses. Theoretical and Applied Genetics 49: 2134.CrossRefGoogle Scholar
Etherton, T. D., Wiggins, J. P., Chung, C. S., Evock, C. M., Rebhun, J. F. and Walton, P. E. 1986. Stimulation of pig growth performance by porcine growth hormone and growth hormone-releasing factor. Journal of Animal Science 63: 13891399.CrossRefGoogle ScholarPubMed
Falconer, D. S. 1973. Replicated selection for body weight in mice. Genetical Research 22: 291321.CrossRefGoogle ScholarPubMed
Farm Animal Welfare Council. 1988. Report on priorities in animal welfare research and development. Farm Animal Welfare Council, Tolworth.Google Scholar
Ferrell, C. L. and Jenkins, T. G. 1984. Energy utilization by mature, non-pregnant, nonlactating cows of different types. Journal of Animal Science 58: 234243.CrossRefGoogle Scholar
Fisher, A. V., Wood, J. D. and Whelehan, O. P. 1986. The effects of a combined androgenic-oestrogenic anabolic agent in steers and bulls. 1. Growth and carcass composition. Animal Production 42: 203211.Google Scholar
Foster, D. O. and Frydman, M. L. 1978. Non-shivering thermogenesis in the rat. 2. Measurements of blood flow with microspheres point to brown adipose tissue as the dominant site of the calorigenesis induced by noradrenaline. Canadian Journal of Physiology and Pharmacology 56: 110122.CrossRefGoogle Scholar
Fowler, R. E. 1958. The growth and carcass composition of strains of mice selected for large and small body size. Journal of Agricultural Science, Cambridge 51: 137148.CrossRefGoogle Scholar
Fowler, V. R., Bichard, M. and Pease, A. 1976. Objectives in pig breeding. Animal Production 23: 365387.Google Scholar
Goldspink, D. F. and Kelly, F. J. 1984. Protein turnover and growth in the whole-body, liver and kidney of the rat from foetus to senility. Biochemical Journal 217: 507576.CrossRefGoogle ScholarPubMed
Goldspink, D. F., Lewis, S. E. M. and Kelly, F. J. 1984. Protein synthesis during the developmental growth of the small and large intestine of the rat. Biochemical Journal 217: 527534.CrossRefGoogle ScholarPubMed
Hammer, R. E., Brinster, R. L., Rosenfeld, M. G., Evans, R. M. and Mayo, K. E. 1985. Expressions of human growth hormone-releasing factor in transgenic mice results in increased somatic growth. Nature, London 315: 413416.CrossRefGoogle ScholarPubMed
Hammond, J. 1947. Animal breeding in relation to nutrition and environmental conditions. Biological Reviews 22: 195213.CrossRefGoogle ScholarPubMed
Hanrahan, J. R. ed. 1987. Beta-agonists and Their Effects on Animal Growth and Carcass Quality. Elsevier, London.Google Scholar
Hayes, J. F. and McCarthy, J. C. 1976. The effects of selection at different ages for high and low body weight on the pattern of fat deposition in mice. Genetical Research 27: 389403.CrossRefGoogle ScholarPubMed
Haysson, V. and Lacy, R. C. 1985. Basal metabolic rate in mammals: taxonomic differences in the allometry of BMR and body mass. Comparative Biochemistry and Physiology 81: 741754.CrossRefGoogle Scholar
Heusner, A. A. 1982. Energy metabolism and body size. 1. Is the 0·75 mass exponent of Kleiber's equation a statistical artefact? Respiration Physiology 48: 112.Google Scholar
Huntington, G. B. and McBride, B. W. 1988. Ruminant splanchic tissues: energy costs of absorption and net metabolism. In Biomechanisms Regulating Growth and Development (ed. Steffens, G. L. and Rumsay, T. S.), pp. 313328. Kliuwer, Boston.CrossRefGoogle Scholar
Huxley, J. S. 1932. Problems of Relative Growth. Methuen, London.Google Scholar
Kempster, A. J., Croston, D., Guy, D. R. and Jones, D. W. 1987. Growth and carcass characteristics of crossbred lambs by ten sire breeds, compared at the same estimated carcass subcutaneous fat proportion. Animal Production 44: 8398.Google Scholar
Kielanowski, J. 1976. Energy cost of protein deposition. In Protein Metabolism and Nutrition (ed. Cole, D. J. A., Boorman, K. N., Buttery, P. J., Lewis, D., Neale, R. J. and Swan, H.), pp. 207215. Butterworths, London.Google Scholar
Kirkwood, J. K. 1981. Bioenergetics and growth in the kestrel (Falco tinnunculus). Ph.D. Thesis, University of Bristol.Google Scholar
Kirkwood, J. K. 1985. Patterns of growth in primates. Journal of Zoology 205: 123136.CrossRefGoogle Scholar
Kirkwood, J. K. and Webster, A. J. F. 1984. Energy-budget strategies for growth in mammals and birds. Animal Production 38: 147155.Google Scholar
Kleiber, M. 1961. The Fire of Life. Wiley, New York.Google Scholar
Koong, L. J., Ferrell, C. L. and Nienaber, J. A. 1985. Assessment of the interrelationships among levels of intake and production, organ size and fasting heat production in growing animals. Journal of Nutrition 115: 13831390.CrossRefGoogle ScholarPubMed
Lang, B. J. and Legates, J. E. 1969. Rate, composition and efficiency of growth in mice selected for large and small body weight. Theoretical and Applied Genetics 39: 306314.CrossRefGoogle ScholarPubMed
Large, R. V. 1976. The influence of reproductive rate on the efficiency of meat production in animal populations. In Meat Animals, Growth and Productivity (ed. Lister, D., Rhodes, D. N., Fowler, V. R. and Fuller, M. F.), pp. 4355. Plenum Press, London.CrossRefGoogle Scholar
Lewis, S. A. M., Kelly, F. J. and Goldspink, D. F. 1984. Pre- and post-natal growth and protein turnover i n smooth muscle, heart and slow and fast twitch skeletal muscles of the rat. Biochemical Journal 217: 517526.CrossRefGoogle Scholar
Lister, D. 1984. In Vivo Measurements of Body Composition in Meat Animals. Elsevier Applied Science.Google Scholar
Lobley, G. E., Connell, A., Mollison, G. S., Brewer, A., Harris, C. I., Buchan, V. and Galbraith, H. 1985. The effects of a combined implant of trenbolone acetate and oestradiol-17p on protein and energy metabolism in growing beef steers. British Journal of Nutrition 54: 681694.CrossRefGoogle Scholar
McPhee, C. P. and Neil, A. R. 1976. Changes in the body composition of mice selected for high and low eight-week weight. Theoretical and Applied Genetics 47: 2126.CrossRefGoogle ScholarPubMed
Milligan, L. P. 1971. Energetic efficiency and metabolic transformations. Federation Proceedings 30: 14541458.Google ScholarPubMed
Milligan, L. P. and McBride, B. W. 1985. Energy costs of ion pumping by animal tissues. Journal of Nutrition 115: 13741382.CrossRefGoogle ScholarPubMed
Palmiter, R. D. and Brinster, R. L. 1985. Transgenic mice. Cell 41: 343345.CrossRefGoogle ScholarPubMed
Prescott, N. J., Wathes, C. M., Kirkwood, J. K. and Perry, G. C. 1985. Growth, food intake and development in broiler cockerels raised to maturity. Animal Production 41: 239245.Google Scholar
Pullar, J. D. and Webster, A. J. F. 1977. The energy costs of protein and fat deposition in the rat. British Journal of Nutrition 37: 355363.CrossRefGoogle ScholarPubMed
Radcuffe, J. D. and Webster, A. J. F. 1978. Sex, body composition and regulation of food intake during growth in the Zucker rat. British Journal of Nutrition 39: 483492.CrossRefGoogle Scholar
Radcuffe, J. D. and Webster, A. J. F. 1979. The effect of varying the quality of dietary protein and energy on food intake and growth in the Zucker rat. British Journal of Nutrition 41: 111124.CrossRefGoogle Scholar
Reeds, P. J. 1988. Comparative aspects of protein metabolism. In Comparative Nutrition (ed. Blaxter, K. L. and MacDonald, I.), pp. 5470. Libbey, London.Google Scholar
Robertson, A. ed. 1980. Selection Experiments in Laboratory and Domestic Animals. Commonwealth Agriculture Bureaux, Slough.Google Scholar
Roche, J. F. and O'callaghan, D. 1984. Manipulation of Growth in Farm Animals. Martinus Nijhoff, Lancaster.CrossRefGoogle Scholar
Russel, A. J. F. and Wright, I. A. 1983. Factors affecting maintenance requirements of beef cows. Animal Production 37: 329334.Google Scholar
Simpson, A. M., Webster, A. J. F., Smith, J. S. and Simpson, C. A. 1978. The efficiency of utilisation of dietary energy for growth in sheep (Ovis ovis) and red deer (Cervus elaphus). Comparative Biochemistry and Physiology 59A: 9599.CrossRefGoogle Scholar
Southgate, J. R., Cook, G. L. and Kempster, A. J. 1982. A comparison of the progeny of British Friesian dams and different sire breeds in 16- and 24-month beef production systems. 1. Live-weight gain and efficiency of food utilization. Animal Production 34: 155166.Google Scholar
Southgate, J. R., Cook, G. L. and Kempster, A. J. 1988. Evaluation of British Friesian, Canadian Holstein and beef breed × British Friesian steers slaughtered over a commercial range of fatness from 16-month and 24-month beef production systems. 1. Live-weight gain and efficiency of food utilization. Animal Production 46: 353364.CrossRefGoogle Scholar
Spencer, G. S. G., Garssen, G. J. and Hart, I. C. 1983. A novel approach to growth promotion using auto-immunisation against somatostatin. I. Effects on growth and hormone levels in lambs. Livestock Production Science 10: 2537.CrossRefGoogle Scholar
Taylor, St. C. S. 1965. A relation between mature weight and the time taken to mature in mammals. Animal Production 7: 203220.Google Scholar
Taylor, St. C. S. 1980. Genetic size-scaling rules in animal growth. Animal Production 30: 161165.Google Scholar
Taylor, St C. S., Thiessen, R. B. and Murray, J. 1986. Inter-breed relationship of maintenance efficiency t o milk yield in cattle. Animal Production 43: 3761.Google Scholar
Walstra, P. 1980. Growth and carcass composition from birth to maturity in relation to feeding level and sex in Dutch Landrace pigs. Mededeligen Landbouwhogeschool, Wageningen, Nederland, pp. 80–84.Google Scholar
Warris, P. D. and Kestin, S. C. 1988. Beta-agonists improve the carcass but may reduce meat quality in sheep. Animal Production 46: 502 (Abstr.).Google Scholar
Webster, A. J. F. 1978. Prediction of the energy requirements for growth in beef cattle. World Review of Nutrition and Dietetics 30: 189227.Google ScholarPubMed
Webster, A. J. F. 1980a. The energetic efficiency of growth. Livestock Production Science 7: 243252.CrossRefGoogle Scholar
Webster, A. J. F. 1980b. The energy costs of digestion and metabolism in the gut. In Digestive Physiology and Metabolism in Ruminants (ed. Ruckebusch, Y. and Thivend, P.), pp. 423438. MTP Press, Lancaster.Google Scholar
Webster, A. J. F. 1983. Energetics of maintenance and growth. In Mammalian Thermogcnesis (ed. Girardier, L. and Stock, M. J.), pp. 178207. Chapman and Hall, London.CrossRefGoogle Scholar
Webster, A. J. F. 1985. Differences in the energetic efficiency of animal growth. Journal of Animal Science 61: Suppl. 2, pp. 92103.Google Scholar
Webster, A. J. F. 1987. Meat and right, farming as if the animal mattered. Canadian Veterinary Journal 28: 462466.Google ScholarPubMed
Webster, A. J. F. 1988a. Comparative aspects of the energy exchange. In Comparative Nutrition (ed. Blaxter, K. L. and MacDonald, I.), pp. 3753. Libbey, London.Google Scholar
Webster, A. J. F. 1988b. Beef cattle and veal calves. In Management and Welfare of Farm Animals, pp. 4779. The Universities Federation of Animal Welfare Handbook. Bailliere Tindall, London.Google Scholar
Webster, A. J. F., Ahmed, A. A. M. and Frappell, J. P. 1982. A note on growth rates and maturation rates in beef bulls. Animal Production 35: 281284.Google Scholar
Wenk, C., Buchmann, M., Hofstetter, P. and Kunz, P. 1988. Beta-agonists in growing lambs: effect on growth performance and energy utilisation. Proceedings of 11th Symposium on Energy Metabolism of Farm Animals. EAAP Publication. In press.Google Scholar
Wood, J. D., Jones, R. C. D., Francombe, M. A. and Whelehan, O. P. 1986. The effects of fat thickness and sex on pig meat quality with special reference to the problems associated with overleanness. 2. Laboratory and trained taste panel results. Animal Production 43: 535544.Google Scholar
Wright, I. A. and Russel, A. J. F. 1984. Partition of fat, body composition and body condition score in mature cows. Animal Production 38: 2332.Google Scholar