Hostname: page-component-77c89778f8-sh8wx Total loading time: 0 Render date: 2024-07-16T18:45:23.980Z Has data issue: false hasContentIssue false
  • English
  • Français

Effects of hydrolyzed yeast supplementation in calf starter on immune responses to vaccine challenge in neonatal calves

Published online by Cambridge University Press:  26 January 2011

M. H. Kim ,
J. K. Seo ,
C. H. Yun ,
S. J. Kang ,
J. Y. Ko  and
J. K. Ha
M. H. Kim
Affiliation:
Department of Agricultural Biotechnology and Research Institute for Agriculture and Life Sciences, College of Agriculture and Life Sciences, Seoul National University, Seoul 151-921, Republic of Korea
J. K. Seo
Affiliation:
Department of Agricultural Biotechnology and Research Institute for Agriculture and Life Sciences, College of Agriculture and Life Sciences, Seoul National University, Seoul 151-921, Republic of Korea
C. H. Yun
Affiliation:
Department of Agricultural Biotechnology and Research Institute for Agriculture and Life Sciences, College of Agriculture and Life Sciences, Seoul National University, Seoul 151-921, Republic of Korea Center for Agricultural Biomaterials, Seoul National University, 599 Gwanangno, Gwanak-gu, Seoul 151-921, Republic of Korea
S. J. Kang
Affiliation:
Dairy Science Division, National Institute of Animal Science, Cheonan 330-801, Republic of Korea
J. Y. Ko
Affiliation:
R&D center, Livestock Research Institute, National Agricultural Cooperative Federation, Anseong, Republic of Korea
J. K. Ha*
Affiliation:
Department of Agricultural Biotechnology and Research Institute for Agriculture and Life Sciences, College of Agriculture and Life Sciences, Seoul National University, Seoul 151-921, Republic of Korea
*
†E-mail: jongha@snu.ac.kr
Get access

Abstract

The effects of hydrolyzed yeast supplementation on growth performance, health and immune-physiological parameters in neonatal calves challenged with vaccine were investigated. Twelve Holstein calves were started in the experiment at 2 ± 1 days of age and were studied for 35 days. Calves were randomly assigned to each of two dietary treatments, a control (CON) and hydrolyzed yeast (HY) group. The calves in the HY group received control calf starter supplemented with 0.2% HY. All calves were given calf starter ad libitum for 5 weeks starting in week 1. Calves were also given whole milk according to a step-down milking protocol. In order to induce immune responses, all calves were challenged with Hog cholera and Erysipelothrix insidiossa live vaccines by intramuscular injection at 3 weeks of age. Growth performance and feed intake were not affected by dietary treatment throughout the experimental period, except that the HY group had significantly higher (P < 0.05) milk intake than did the CON group at 3 weeks of age. Calves in the HY group showed significantly better (P < 0.05) fecal and health scores at 3 weeks compared to those in the control group. After vaccine challenge, neutropenia, lymphophilia and thrombocytopenia were observed in the CON group, but calves in the HY group did not show significant changes of leukocytes. The average concentration of serum haptoglobin in the HY group was significantly higher (P < 0.05) at 1 and 3 days post-vaccine challenge (DPVC) than that of CON group. Feeding HY supplemented calf starter resulted in a higher (P < 0.05) relative amount of bacterial and viral – specific IgA than in the CON group at 5 DPVC. Although the percentage of CD4+ T cells was significantly (P < 0.05) higher in the HY group than in the CON group at −2 DPVC, significant differences between groups after vaccine challenge was not observed during the experimental period. These results suggest that 0.2% HY supplementation in calf starter can improve the health status and immune-related serum protein production and affect blood cell composition in neonatal calves after vaccine challenge.

Keywords

neonatal calfhydrolyzed yeastimmune
Type
Full Paper
Information
animal , Volume 5 , Issue 6 , June 2011 , pp. 953 - 960
Copyright
Copyright © The Animal Consortium 2011

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

Footnotes

a

Both authors equally contributed as the first author of this article.

References

Bradford, MM 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Analytical Biochemistry 72, 248–254.CrossRefGoogle ScholarPubMed
Caccavo, D, Pellegrino, N, Altamura, M, Rigon, A, Luigi, A, Amoroso, A, Jirillo, E 2002. Antimicrobial and immunoregulatory functions of lactoferrin and its potential therapeutic application. Journal of Endotoxin Research 8, 403–417.Google ScholarPubMed
Callaway, ES, Martin, SA 1997. Effects of a Saccharomyces cerevisiae culture on ruminal bacteria that utilize lactate and digest cellulose. Journal of Dairy Science 80, 2035–2044.Google Scholar
Dann, HM, Drackley, JK, McCoy, GC, Hutjems, MF, Garrett, JE 2000. Effects of yeast culture (Saccaromyces cerevisiae) on prepartum intake and postpartum intake and milk production of Jersey cows. Journal of Dairy Science 8, 123–127.Google Scholar
Daniele, M, Jair, DAM, Daniele, P, Polyana, PR 2009. Bermuda grass hay or dorghum silage with or without yeast addition on performance and carcass characteristics of crossbred young bulls finished in feedlot. Asian-Australasian Journal of Animal Science 22, 206–215.Google Scholar
Davis, ME, Maxwell, CV, Erf, GF, Brown, DC, Wistuba, TJ 2004. Dietary supplementation with phosphorylated mannans improves growth response and modulates immune function of weanling pigs. Journal of Animal Science 82, 1882–1891.Google Scholar
Davis, ME, Maxwell, CV, Brown, DC, de Rodas, BZ, Johnson, ZB, Kegley, EB, Hellwig, DH, Dvorak, RA 2002. Effect of dietary mannan oligosaccharide and (or) pharmacological additions of copper sulfate on growth performance and immunocompetence of weanling and growing/finishing pigs. Journal of Animal Science 80, 2887–2894.CrossRefGoogle ScholarPubMed
Djeraba, A, Quere, P 2000. In vivo macrophage activation in chickens with acemannan, a complex carbohydrate extracted from Aloe vera. International Journal of Immunopharmacology 22, 365–372.CrossRefGoogle ScholarPubMed
Emmanuel, DGV, Jafari, A, Beauchemin, KA, Leedle, JAZ, Ametaj, BN 2007. Feeding live culture of Enterococcus facium and Saccharomyces cerevisiae induces and inflammatory response in feedlot steers. Journal of Animal Science 85, 233–239.Google Scholar
Feng, J, Liu, X, Xu, ZR, Lu, YP, Liu, YY 2007. Effect of fermented soybean meal on intestinal morphology and digestive enzyme activities in weaned piglets. Digestive Diseases and Sciences 53, 1845–1850.Google Scholar
Galvão, KN, Santos, JEP, Coscioni, A, Villasenor, M, Sischo, WM, Berge, ACB 2005. Effect of feeding live yeast products to calves with failure of passive transfer on performance and patterns of antibiotic resistance in fecal Escherichia coli. Reproduction Nutrition Development 45, 427–440.Google Scholar
Godbout, JP, Glaser, R 2006. Stress-induced immune dysregulation: implications for wound healing, infectious disease and cancer. Journal of Neuroimmune Pharmacology 1, 421–427.Google Scholar
Hickey, MC, Drennan, M, Earley, B 2003. The effect of abrupt weaning of suckler calves on the plasma concentrations of cortisol, catecholamines, leukocytes, acute-phase proteins and in vitro interferon-gamma production. Journal of Animal Science 81, 2847–2855.CrossRefGoogle ScholarPubMed
Jensen, GS, Patterson, KM, Yoon, I 2008. Nutritional yeast culture has specific anti-microbial properties without affecting healthy flora. Preliminary Results. Journal of Animal and Feed Sciences 17, 247–252.CrossRefGoogle Scholar
Kahn, CM 2005. The Merck Veterinary Manual, 9th edition. Merck & Co., Inc., Whitehouse station, New jersey.Google Scholar
Kauf, ACW, Rosenbusch, RF, Paape, MJ, Bannerman, DD 2007. Innate immune response to intramammary Mycoplasma bovis infection. Journal of Dairy Science 90, 3336–3348.Google Scholar
Khan, MA, Lee, HJ, Lee, WS, Kim, HS, Kim, SB, Ki, KS, Ha, JK, Lee, HG, Choi, YJ 2007. Pre- and post-weaning performance of Holstein female calves fed milk through step-down and conventional methods. Journal of Dairy Science 90, 876–885.CrossRefGoogle Scholar
Kim, MH, Yun, CH, Ko, JY, Kang, JS, Kim, HS, Kang, SJ, Lee, WS, Kim, JH, Ha, JK 2009. Changes of immunophysiological characteristics in neonatal calves experimentally challenged with mixture of live bacteria and virus. Journal of Dairy Science 92, 5534–5543.CrossRefGoogle ScholarPubMed
Kumar, U, Sareen, VK, Singh, S 1997. Effect of yeast culture supplementation on ruminal microbial populations and metabolism in buffalo calves fed a high roughage diet. Journal of the Science Food and Agriculture 73, 231–236.Google Scholar
Larson, LL, Owen, FG, Albright, JL, Appleman, RD, Lamb, RC, Muller, LD 1977. Guidelines toward more uniformity in measuring and reporting calf experimental data. Journal of Dairy Science 60, 989–991.CrossRefGoogle Scholar
Lesmeister, KE, Heinrichs, AJ, Gabler, MT 2004. Effects of supplemental Yeast (Saccharomyces cerevisiae) culture on rumen development, growth characteristics, and blood parameters in neonatal dairy calves. Journal of Dairy Science 87, 1832–1839.Google Scholar
Magalhães, VJA, Susca, F, Lima, FS, Branco, AF, Yoon, I, Santos, JEP 2008. Effect of feeding yeast culture on performance, health, and immunocompetence of dairy calves. Journal of Dairy Science 91, 1497–1509.Google Scholar
Murphy, EA, Davis, JM, Brown, AS, Carmichael, MD, Ghaffar, A, Mayer, EP 2007. Oat beta-glucan effects on neutrophil respiratory burst activity following exercise. Medicine and Science in Sports and Exercise 39, 639–644.CrossRefGoogle ScholarPubMed
Nonnecke, BJ, Foote, MR, Smith, JM, Pesch, BA, Van Amburgh, ME 2003. Composition and functional capacity of blood mononuclear leukocyte populations from neonatal calves on standard and intensified milk replacer diets. Journal of Dairy Science 86, 3592–3604.CrossRefGoogle ScholarPubMed
Pérez-Sotelo, LS, Talavera-Rojas, M, Monroy-Salazar, HG, Lagunas-Bernabé, S, Cuarón-Ibargüengoytia, JA, Jiménez, RMO, Vázquez-Chagoyán, JC 2005. In vitro evaluation of the binding capacity of Saccharomyces cerevisiae Sc47 to adhere to the wall of Salmonella spp. Revista latinoamericana de microbiologia 47, 70–75.Google Scholar
Quigley, JD III, Wallis, LB, Dowlen, HH, Heitmann, RN 1992. Sodium bicarbonate and yeast culture effects on ruminal fermentation, growth, and intake in dairy calves. Journal of Dairy Science 75, 3531–3538.Google Scholar
SAS Institute 2001. SAS/STAT user's guide. Version 8.2 ed. SAS Institute, Inc., Cary, NC.Google Scholar
Savage, TF, Cotter, PF, Zakrzewska, EI 1996. The effect of feeding mannan oligosaccharide on immunoglobulins, plasma IgG and bile IgA of Wrolstad MW male turkeys. Poultry Science 75 (suppl. 1), 143.Google Scholar
Selijelid, R, Rasmussen, LT, Larm, O, Hoffman, J 1987. The protective effect of beta 1-3d-glucan-derivatized plastic beads against Eschericia coli infection in mice. Scandinavian Journal of Immunology 25, 55–60.Google Scholar
Seymour, WM, Nocek, JE, Siciliano-Jones, J 1995. Effects of a colostrum substitute and of dietary brewer's yeast on the health and performance of dairy calves. Journal of Dairy Science 78, 412–442.Google Scholar
Shen, YB, Piao, XS, Kim, SW, Wang, L, Liu, P, Yoon, I, Zhen, YG 2009. Effects of yeast culture supplementation on growth performance, intestinal health, and immune response of nursery pigs. Journal of Animal Science 87, 2614–2624.Google Scholar
Spring, P, Wenk, C, Dawson, KA, Newman, KE 2000. The effects of dietary mannan oligosaccharides on cecal parameters and the concentration of enteric bacteria in the ceca of Salmonella-challenges broiler chicks. Poultry Science 79, 205–211.CrossRefGoogle Scholar
Suffrendini, AF, Fantuzzi, G, Badolato, R, Oppenheim, JJ, O'grady, NP 1999. New insights into the biology of the acute phase response. Journal of Clinical Immunology 19, 203–214.Google Scholar
Wagner, DG, Quinonez, J, Bush, LJ 1990. The effect of corn or wheat-based diets and yeast culture on performance, ruminal pH, and volatile fatty acids in dairy calves. Agri-Practice 11, 7–12.Google Scholar
Wang, T, Yong-Ming, FU, Jun-Long, Lv 2003. Effects of mini-peptides on the growth performance and the development of small intestines in weaning piglets. Animal Husbandry Veterinary Medical 4–8.Google Scholar
Wang, Z, Guo, Y, Yuan, J, Zhang, B 2008. Effect of dietary β-1,3/1,6-glucan supplementation on growth performance, immune response and plasma prostglandin E2, growth hormone and ghrelin in weaning piglets. Asian-Australasian Journal of Animal Science 21, 707–714.Google Scholar
White, LA, Newman, MC, Cromwell, GL, Lindemann, MD 2002. Brewers dried yeast as a source of mannan oligosaccharides for weanling pigs. Journal of Animal Science 80, 2619–2628.Google ScholarPubMed
Williams, PEV, Tait, CAG, Innes, GM, Newbold, CJ 1991. Effects of the inclusion of yeast culture (Saccharomyces cerevisiae plus growth medium) in the diet of dairy cows on milk yield and forage degradation and fermentation patterns in the rumen of steers. Journal of Animal Science 69, 3016–3026.Google Scholar