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Leptin and obesity
Published online by Cambridge University Press: 11 September 2013
In a nutshell
Leptin is a hormone released from fat that ‘signals’ the body's fat level, decreases appetite and food intake and increases energy expenditure. It also affects CVS and other systems.
Some therapeutic trials of leptin injections for obesity have been conducted with mixed results. Apart from rare cases of leptin deficiency, potential uses may include preventing weight rebound after weight reduction and treating lipodystrophy.
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- Copyright © Cambridge University Press 2006