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Neural transplants are grey matters

Published online by Cambridge University Press:  04 February 2010

Britt Anderson
Affiliation:
Department of Neurology, University of Alabama School of Medicine, Birmingham, AL 35294;
Anjan Chatterjee
Affiliation:
Department of Neurology, University of Alabama School of Medicine, Birmingham, AL 35294;
George Graham
Affiliation:
Philosophy Department, University of Alabama at Birmingham, Birmingham, AL 35294. arhu006@uab.dpo

Abstract

The lesion and transplantation data cited by Sinden et al., when considered in tandem, seem to harbor an internal inconsistency, raising questions of false localization of function. The extrapolation of such data to cognitive impairment and potential treatment strategies in Alzheimer's disease is problematic. Patients with focal basal forebrain lesions (e.g., anterior communicating artery aneurysm rupture) might be a more appropriate target population.

Type
Open Peer Commentary
Copyright
Copyright © Cambridge University Press 1995

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