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The absorption and distribution of the naturally occurring tocochromanols in the rat

Published online by Cambridge University Press:  09 March 2007

C. K. Pearson  and
M. McC. Barnes
C. K. Pearson
Affiliation:
Department of Biochemistry, University of Liverpool
M. McC. Barnes
Affiliation:
Department of Biochemistry, University of Liverpool
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Abstract

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1. Groups of female albino rats were given 12–20 mg of one of the eight known toco-chromanols in 0.2 ml arachis oil by stomach tube, and were killed 2, 4, 8, 16 or 24 h afterwards. The liver, spleen, heart, kidneys, brain, small intestine and a portion of striated muscle were removed from each rat and analysed for the tocochromanol given.

3. Maximum levels of the tocochromanols occurred in most tissues 4–8 h after dosing. In the liver the tocopherols were more efficiently absorbed than were the corresponding toco-trienols. In kidney, heart and muscle the percentage uptake of the tocotrienols was often greater than that of the corresponding tocopherols.

Type
Research Article
Information
British Journal of Nutrition , Volume 24 , Issue 2 , June 1970 , pp. 581 - 587
Copyright
Copyright © The Nutrition Society 1970

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