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Absorption and metabolism of the volatile fatty acids in the hind-gut of the rabbit

Published online by Cambridge University Press:  09 March 2007

Josette Marty  and
Michele Vernay
Josette Marty
Affiliation:
Institut de Physiologie, 2 rue F. Magendie, 31400–Toulouse, France
Michele Vernay
Affiliation:
Institut de Physiologie, 2 rue F. Magendie, 31400–Toulouse, France
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Abstract

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1. Volatile fatty acids (VFA) absorption in the large intestine of the anaesthetized rabbit was evaluated by measuring variations in the concentration of VFA in intestinal loops and plasma arteriovenous differences. Metabolic conversions were studied using [1-14C]acetate, [1-14C]propionate and [3,4-14C]butyrate.

2. The hind-gut tissues metabolized the three VFA, although this metabolism varied with the segment studied. Butyrate was the best respiratory fuel for the colonic wall, followed by propionate; acetate participated also, but it was mainly converted to glutamate.

3. The liver was the main organ metabolizing absorbed propionate and butyrate; acetate was available for extrahepatic tissue metabolism.

4. For the rabbit, VFA represented about 40% of the maintenance energy requirement.

Type
Papers on General Nutrition
Information
British Journal of Nutrition , Volume 51 , Issue 2 , March 1984 , pp. 265 - 277
Copyright
Copyright © The Nutrition Society 1984

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