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Body iron and its distribution between haem and non-haem fractions in the suckling rat

Published online by Cambridge University Press:  09 March 2007

A. J. Leslie  and
I. Kaldor
A. J. Leslie
Affiliation:
Department of Physiology, The University of Western Australia, Nedlands, Western Autralia, 6009
I. Kaldor
Affiliation:
Department of Physiology, The University of Western Australia, Nedlands, Western Autralia, 6009
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Abstract

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1. Total body iron and some of its subfractions, i.e. haem iron, non-haem iron and ferritin iron, as well as ferritin were measured in groups of newborn rats and of rats aged 4,15 and 24 d.

2. Iron accumulated in the rats throughout suckling, with slightly more going into the haem than into the non-haem fraction.

3. Per unit body-weight, haem iron was maintained well throughout the study period but total body iron and non-haem iron were both significantly diminished at 15 d.

4. Within the non-haem fraction, ferritin iron was severely diminished at both 15 and 24 d, but the non-ferritin portion of non-haem iron was increased.

5. The results were interpreted in terms of the relationship between the growth of body mass and the supply of iron to the young animal.

Type
General Nutrition
Information
British Journal of Nutrition , Volume 26 , Issue 3 , November 1971 , pp. 469 - 475
Copyright
Copyright © The Nutrition Society 1971

References

REFERENCES

Bruner, H. D., Van de Erve, J. & Carlson, A. J. (1938). Am. J. Physiol. 124, 620.CrossRefGoogle Scholar
Drabkin, D. L. & Fitz-Hugh, T. Jr (1934). Am. J. Physiol. 108, 61.Google Scholar
Ezekiel, E. (1967). J. Lab. clin. Med. 70, 138.Google Scholar
Greenberg, A. & Erickson, D. (1944). J. biol. Chem. 156, 679.CrossRefGoogle Scholar
Hahn, P. F. & Whipple, G. H. (1936). Am. J. med. Sci. 191, 24.Google Scholar
Hallgren, B. (1954). Acta Soc. Med. upsalien. 59, 79.Google Scholar
Huggett, A.St, G. & Widdas, W. F. (1949). J. Physiol., Lond. 110, 386.Google Scholar
Kaldor, I. (1958). Aust. J. exp. Biol. med. Sci. 36, 173.CrossRefGoogle Scholar
Leslie, A. J. & Kaldor, I. (1970). Analyt. Biochem. 37, 64.Google Scholar
Leslie, A. J. & Kaldor, I. (1971). Am. J. Physiol. 220, 1000.Google Scholar
Loh, T. T. & Kaldor, I. (1971). Biol. Neonate 17, 173.Google Scholar
McCance, R. A. & Widdowson, E. M. (1951). J. Physiol., Lond. 112, 450.CrossRefGoogle Scholar
Mazur, A. & Shorr, E. (1950). J. biol. Chem. 182, 607.CrossRefGoogle Scholar
Morgan, E. H. (1961). J. Physiol., Lond. 158, 573.CrossRefGoogle Scholar
Spray, C. M. & Widdowson, E. M. (1950). Br. J. Nutr. 4, 332.CrossRefGoogle Scholar
Torrance, J. D., Charlton, R. W., Schmaman, A., Lynch, S. R. & Bothwell, T. H. (1968). J. clin. Path. 21, 495.CrossRefGoogle Scholar