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The effect of molybdenum levels in sorghum (Sorghum vulgare Pers.) on uric acid and copper excretion in man

Published online by Cambridge University Press:  09 March 2007

Y. G. Deosthale  and
C. Gopalan
Y. G. Deosthale
Affiliation:
National Institute of Nutrition, Indian Council of Medical Research, Jamai Osmania, Hyderabad-500007, India
C. Gopalan
Affiliation:
National Institute of Nutrition, Indian Council of Medical Research, Jamai Osmania, Hyderabad-500007, India
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Abstract

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1. The effect of various dietary levels of molybdenum on uric acid and copper excretion was studied in experiments with four adult men given diets based on two sorghum varieties (Sorghum vulgare Pers.) differing widely in Mo content.

2. With a Mo intake of 160, 540 or 1540 μg/d the urinary excretion of uric acid was unaltered.

3. The excretion of Cu in urine increased with increasing Mo intake.

4. Cu-balance studied with high- and low-Mo diets showed that with a high-Mo diet urinary Cu excretion increased but faecal Cu was unaffected. This indicates that dietary Mo had no effect on Cu absorption.

5. The high serum concentration of Cu with diets high in Mo indicates that Mo either mobilizes tissue Cu or inhibits Cu uptake, or both.

Type
Clinical and Human Nutrition
Information
British Journal of Nutrition , Volume 31 , Issue 3 , May 1974 , pp. 351 - 355
Copyright
Copyright © The Nutrition Society 1974

References

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