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The influence of guar-gum bread on the regulation of diabetes mellitus type II in elderly patients

Published online by Cambridge University Press:  09 March 2007

J. P. Sels ,
J. A Flendrig  and
Th. J. Postmes
J. P. Sels
Affiliation:
Department of Internal Medicine, Academic Hospital Maastricht, Postbus 1918, 6201 BX Maastricht, The Netherlands
J. A Flendrig
Affiliation:
Department of Internal Medicine, Academic Hospital Maastricht, Postbus 1918, 6201 BX Maastricht, The Netherlands
Th. J. Postmes
Affiliation:
Department of Internal Medicine, Academic Hospital Maastricht, Postbus 1918, 6201 BX Maastricht, The Netherlands
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Abstract

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1. The effect of a high-fibre bread mixed with guar-gum (75 g/kg flour) on serum glucose, connecting peptide (C-peptide), haemoglobin A1 (HbAI), high-density-lipoprotein-cholesterol (HDL-cholesterol) and triglycerides was examined in fourteen elderly patients with diabetes mellitus type II.

2. The mean daily consumption of guar gum was 8.1 g. Gastrointestinal disorders were not observed.

3. Consumption of guar-gum bread resulted in a significant decrease in C-peptide values on the 1st day and blood glucose values after 3 weeks (both measured 90 min after breakfast). C-peptide values remained low, while an unaccountable ‘rebound’ phenomenon was seen in the blood glucose values 90 min after breakfast at the end of the study.

4. No significant change was seen in respect to HDL-cholesterol and triglycerides. However, a small significant increase in HbAl was noted.

Type
Papers of direct relevance to Clinical and Human Nutrition
Information
British Journal of Nutrition , Volume 57 , Issue 2 , March 1987 , pp. 177 - 183
Copyright
Copyright © The Nutrition Society 1987

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