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Genetic studies of malathion resistance in Anopheles arabiensis Patton (Diptera: Culicidae)

Published online by Cambridge University Press:  10 July 2009

J. D. Lines ,
M. A. E. Ahmed  and
C. F. Curtis
J. D. Lines
Affiliation:
London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK
M. A. E. Ahmed
Affiliation:
London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK
C. F. Curtis
Affiliation:
London School of Hygiene and Tropical Medicine, London WC1E 7HT, UK
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Abstract

Crosses of Sudanese strains of Anopheles arabiensis Patt. resistant and susceptible to malathion indicated that the resistance was incompletely dominant. The results of tests of male progeny of successive backcrosses agreed well with the hypothesis of control of the resistance by a single gene. However, the results from females suggested the additional involvement of a sex-limited modifier. Tests of mixtures initiated with a 1:1 ratio of resistant and susceptible first-instar larvae gave little evidence for selective mortality during the larval stage. However, the mortalities in tests on malathion recorded among adults emerging on successive days from these mixtures, and also from F2 and backcross progenies, indicated that the development of the resistant larvae was significantly faster than that of the susceptible ones. The fact that this occurred in the F2 and backcross progenies indicates that it may be due to a pleiotropic effect of the resistance gene, but it is pointed out that results from much more prolonged backcrossing would be necessary to rule out the possible effects of linked genes.

Type
Original Articles
Information
Bulletin of Entomological Research , Volume 74 , Issue 2 , June 1984 , pp. 317 - 325
Copyright
Copyright © Cambridge University Press 1984

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References

Ayad, H. & Georghiou, G. P. (1975). Resistance to organophosphates and carbamates in Anopheles albimanus based on reduced sensitivity to acetylcholinesterase.—J. econ. Ent. 68, 295–297.CrossRefGoogle ScholarPubMed
Akood, M. A. S. (1980). The use of serology and of tests for drug resistance in studying problems of malaria control in the Sudan.—Ph.D. thesis, Univ. London.Google Scholar
Curtis, C. F., Cook, L. M. & Wood, R. J. (1978). Selection for and against insecticide resistance and possible methods of inhibiting the evolution of resistance in mosquitoes.—Ecol. Entomol. 3, 273–287.CrossRefGoogle Scholar
Davidson, G. & Sawyer, B. (1975). Carbamate and organophosphate resistance in Anopheles albimanus.—Trans. R. Soc. trop. Med. Hyg. 69, 431.Google ScholarPubMed
Emeka-Ejiofor, S. A. I., Curtis, C. F. & Davidson, G. (1983). Tests for effects of insecticide resistance genes in Anopheles gambiae on fitness in the absence of insecticides.—Entomologia exp. appl. 34, 163–168.CrossRefGoogle Scholar
Georghiou, G. P. (1969). Genetics of resistance to insecticides in houseflies and mosquitoes.—Expl Parasit. 26, 224–255.CrossRefGoogle ScholarPubMed
Hemingway, J. (1981). Genetics and biochemistry of insecticide resistance in anophelines.—Ph.D. thesis, Univ. London.Google Scholar
Hemingway, J. (1983 a). Biochemical studies on malathion resistance in Anopheles arabiensis from Sudan.—Trans. R. Soc. trop. Med. Hyg. 77, 477–480.CrossRefGoogle ScholarPubMed
Hemingway, J. (1983 b). The genetics of malathion resistance in Anopheles stephensi from Pakistan.—Trans. R. Soc. trop. Med. Hyg. 77, 106–108.CrossRefGoogle ScholarPubMed
Hemingway, J. & Georghiou, G. P. (in press). Differential suppression of organophosphate resistance in Culex quinquefasciatus by the synergists IBP, DEF and TPP.—Pestic. Biochem. & Physiol.Google Scholar
Herath, P. R. J. & Davidson, G. (1981 a). Studies on the nature of malathion resistance in a population of Anopheles stephensi from southern Iran.—Mosquito News 41, 531–534.Google Scholar
Herath, P. R. J. & Davidson, G. (1981 b). The nature of malathion resistance in a population of Anopheles culicifacies Giles.—Bull. Wld Hlth Org. 59, 383–386.Google Scholar
McKenzie, J. M., Whitten, M. J. & Adena, M. A. (1982). The effect of genetic background on the fitness of diazinon resistance genotypes of the Australian sheep blowfly, Lucilia cuprina.—Heredity 49, 1–9.CrossRefGoogle Scholar
Muggleton, J. (1982). A model for the elimination of insecticide resistance using heterozygous disadvantage.—Heredity 49, 247–251.CrossRefGoogle Scholar
Muggleton, J. (1983). Relative fitness of malathion-resistant phenotypes of Oryzaephilus surinamensis L. (Coleoptera: Silvanidae)—J. appl. Ecol. 20, 245–254.CrossRefGoogle Scholar
Rathor, H. R. & Toqir, G. (1981). Mode of inheritance of malathion resistance in Anopheles stephensi Liston.—Mosquito News 41, 359–367.Google Scholar
Roush, R. T. & Plapp, F. W. Jr. (1982). Effects of insecticide resistance on biotic potential of the house fly (Diptera: Muscidae).—J. econ. Ent. 75, 708–712.CrossRefGoogle ScholarPubMed
Taylor, C. E. & Georghiou, G. P. (1979). Suppression of insecticide resistance by alteration of gene dominance and migration.—J. econ. Ent. 72, 105–109.CrossRefGoogle Scholar
Who (World Health Organization) (1976). Resistance of vectors and reservoirs of disease to pesticides. Twenty-second report of the WHO Expert Committee on Insecticides.—Tech. Rep. Ser. Wld Hlth Org. no. 585, 88 pp.Google Scholar