Hostname: page-component-77c89778f8-vpsfw Total loading time: 0 Render date: 2024-07-22T07:40:20.406Z Has data issue: false hasContentIssue false

Herbert Henri Jasper (1906 – 1999): An Appreciation

Published online by Cambridge University Press:  02 December 2014

William Feindel*
Affiliation:
Montreal Neurological Institute and Hospital, Department of Neurology and Neurosurgery, McGill University, Montreal
Rights & Permissions [Opens in a new window]

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

Herbert Henri Jasper dedicated his life to studies of the brain in relation to the mind and behavior. He pioneered the application of the electroencephalogram (EEG) for the study of the electrical activity of the brain and used this technique in studies of consciousness, learning and particularly the examination of epileptic discharge. He utilized microelectrode recordings from single brain cells and combined this technique with microchemical analyses to study cortical and sub-cortical activity. He added substantially to our understanding of brainstem and thalamic reticular formations in conditions of consciousness and in relation to petit-mal epilepsy. His work with Wilder Penfield and associates over a quarter century elucidated the mechanisms of epilepsy and added to our understanding of the functional anatomy of the human brain. An enthusiastic and able organizer, Herbert Jasper was responsible for many international conferences on brain science and worked tirelessly to develop international collaboration among investigators of the nervous system, being one of the founders of the International Brain Research Organization and the Society for Neuroscience. His prodigious contributions in basic and clinical research will be recognized by the world community of brain science for years to come.

Résumé

RÉSUMÉ

Herbert Henri Jasper a consacré sa vie à l’étude du cerveau et à sa relation avec la conscience et le com- portement. Il fut le pionnier de l’électroencéphalogramme (EEG) servant à l’étude de l’activité cérébrale électrique et a employé cette technique dans différentes études sur la conscience, l’apprentissage et particulièrement la com- préhension des décharges épileptiques. Il a utilisé les données captées par micro-électrodes à partir cellules indi- viduelles du cerveau et a combiné cette technique à des analyses micro-chimiques influencées par l’activité corticale et sub-corticale. Il fut d’une aide considérable à notre compréhension des formations réticulaires du cerveau dans le conscient et concernant l’épilepsie surnommée petit-mal. Son travail de recherche avec Wilder Penfield et ses asso- ciés pendant plus d’un quart de siècle a élucidé les mécanismes de l’épilepsie et a contribué à une meilleure con- naissance du fonctionnement et de l’anatomie du cerveau humain. Un organisateur d’expérience et démontrant tou- jours de l’enthousiasme, Herbert Jasper a été responsable de plusieurs conférences internationales sur la science du cerveau et a travaillé inlassablement à développer une collaboration internationale entre rechercheurs sur le système nerveux, étant lui-même l’un des fondateurs de International Brain Research Organization and Society for Neuroscience. Sa prodigieuse contribution à la recherche clinique sera reconnue par le monde de la science sur le cerveau pour des années à venir.

Type
In Memoriam
Copyright
Copyright © The Canadian Journal of Neurological 1999

References

1. Jasper, H.H. Some highlights of 70 years in neuroscience research. In: Squire, LR, ed. The History of Neuroscience in Autobiography. Vol. 1. Washington, DC: Society for Neuroscience. 1996; 318346.Google Scholar
2. Jasper, H.H. Philosophy or physics – mind or molecules. In: Worden, FG, Swazey, JP, Adelman, G, eds. The Neurosciences: Paths of Discovery. Cambridge, Mass: MIT Press, 1975; 403422.Google Scholar
3. Jasper, H.H. History of the early development of electroencephalog-raphy and clinical neurophysiology at the Montreal Neurological Institute: the first 25 years, 1939–1964. Can J Neurol Sci 1991; 18, No. 4 (Supplement): 533548.Google Scholar
4. Gloor, P. Jasper, H.H., neuroscientist of our century. In: Neurotransmitters and Cortical Function: from Molecules to Mind. Avoli, M, Reader, TA, Dykes, RW, Gloor, P (eds). New York: Plenum, 1988: 113.Google Scholar
5. van Gelder, N.M. Jasper, H.H.: Modern concepts of epilepsy. In: Neurotransmitters and Cortical Function: from Molecules to Mind. Avoli, M, Reader, TA, Dykes, RW, Gloor, P (eds). New York: Plenum, 1988: 1523.Google Scholar
6. Penfield, W. Jasper, Herbert. In: Cordeau, JP, Gloor, P, eds. Recent Contributions to Neurophysiology: International Symposium in Neurosciences in Honor of Herbert H. Jasper. EEG Clin Neurophysiol 1972; Suppl. 31:912.Google Scholar
7. Jasper, H.H., Carmichael, L. Electrical potentials from the intacthuman brain. Science 1935; 81: 5153.Google Scholar
8. Jasper, H.H. Historical introduction: early efforts to find neuro-chemical mechanisms in epilepsy. In: Avanzini, G, Engel, J. Fanello, R, Heinemann, U, eds. Neurotransmitters in Epilepsy. New York: Elsevier Science Publishers, 1992: 18.Google Scholar
9. Penfield, W, Jasper, H. Epilepsy and the Functional Anatomy of theHuman Brain. Boston: Little, Brown, 1954.Google Scholar
10. Jasper, H.H., Bertrand, G. Recording from microelectrodes in stereo-taxic surgery for Parkinson’s disease. J Neurosurg 1966; 24:219221.Google Scholar
11. Bazemore, A.W., Elliott, K.A.C., Florey, E. Factor I and gammaamino-butyric acid. Nature, 1956; 178: 1052–3.Google Scholar
12. Feindel, W. Brain physiology at the Montreal Neurological Institute:some historical highlights. J Clin Neurophysiol 1992; 9(2): 176194.Google Scholar
13. Florey, E. GABA: history and perspectives. Can J Physiol Pharmacol 1991; 69: 1049–56.Google Scholar
14. Jasper, H.H. The early development of neuroscience in Canada. Can J Neurol Sci 1985; 12: 221229.Google Scholar
15. Jasper, H.H. Cortical excitatory state and synchronism in the controlof bioelectric autonomous rhythms. Cold Spring Harb. Symp Quant Biol 1936; 4: 320338.Google Scholar