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Neuropsychological Functioning in Unilateral Cerebellar Damage

Published online by Cambridge University Press:  18 September 2015

Thérèse Botez-Marquard ,
Jean Léveillé  and
M.I. Botez
Thérèse Botez-Marquard*
Affiliation:
Laboratory of Neurobiology, Neurology Service, Hôtel-Dieu de Montréal and Faculty of Medicine, University of Montréal, Montréal
Jean Léveillé
Affiliation:
Laboratory of Neurobiology, Neurology Service, Hôtel-Dieu de Montréal and Faculty of Medicine, University of Montréal, Montréal
M.I. Botez
Affiliation:
Laboratory of Neurobiology, Neurology Service, Hôtel-Dieu de Montréal and Faculty of Medicine, University of Montréal, Montréal
*
Laboratory of Neurobiology, Neurology Service, Hôtel-Dieu de Montréal, 3840 St, Urbain Street, Montréal, Québec, Canada H2W IT8
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Abstract:

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A woman had a left superior cerebellar artery infarct associated with reduced hexamethyl-propileneamine oxime uptake on SPECT scan of the basal ganglia and frontoparietal areas of the opposite hemisphere performed poorly in some neuropsychological tests indicating right hemisphere dysfunction. There was a lengthening of reaction and movement times with the hand ipsilateral to the lesion. These deficits were temporary. A unilateral cerebellar lesion can produce neuropsychological deficits, possibly because of hypoperfusion in contralateral frontoparietal regions, but spontaneous neuropsychological remissions may occur.

Résumé:

Résumé:

Fonction neuropsychologique avec une lésion cérébelleuse unilatérale. Il s’agit d’une patiente ayant eu un accident cérébro-vasculaire suite à une thrombose de l’artère cérébelleuse supérieure et qui a présenté une diaschisis cerebello-corticale à la scintitomographie (SPECT) avec hexamethylpropileneamine oxime (HMPAO). L’évaluation neuropsychologique a été suggestive d’une dysfonction frontopariétale droite, la même localisation que celle de 1’hypoperfusion constatée au SPECT. Une lésion cérébelleuse unilatérale peut déterminer des déficits suggestifs d’une dysfonction neuropsychologique frontopariétale contralatérale en présence d’un scan normal.

Type
Original Articles
Information
Canadian Journal of Neurological Sciences , Volume 21 , Issue 4 , November 1994 , pp. 353 - 357
Copyright
Copyright © Canadian Neurological Sciences Federation 1994

References

REFERENCES

1. Botez, MI, Gravel, J, Attig, E and Vézina, JL. Reversible chronic cerebellar ataxia after phenytoin intoxication: possible role of cerebellum in cognitive thought. Neurology 1985; 35: 1152–1157.CrossRefGoogle ScholarPubMed
2. Botez, MI, Botez, T, Elie, R and Attig, E. Role of the cerebellum in complex human behavior. Ital J Neurol Sci 1989; 10: 291–300.CrossRefGoogle ScholarPubMed
3. Botez, MI, Léveillé, J and Botez, T. Role of the cerebellum in cognitive thought: SPECT and neurological findings. In: Matheson, M. and Newman, H., eds. Rehabilitation: The Path Back, Australian Society for the Study of Brain Impairment, Richmond, Australia, 1989.Google Scholar
4. Bracke-Tolkmitt, R, Linden, A, Canavan, AGM, et al. The cerebellum contributes to mental skills. Behav Neurosci 1989; 103: 442–446.CrossRefGoogle Scholar
5. Kish, S, El-Awar, M, Schut, L, et al. Cognitive deficits in olivopontocerebellar atrophy: implications for the cholinergic hypothesis of Alzheimer dementia. Ann Neurol 1988; 24: 200–206.CrossRefGoogle Scholar
6. Appollonio, IM, Grafman, J, Schwartz, V, Massaquoi, S and Hallett, M. Memory in patients with cerebellar degeneration. Neurology 1993; 43: 1536–1544.CrossRefGoogle ScholarPubMed
7. El-Awar, M, Kish, S, Oscar-Berman, M, et al. Selected delayed alternation deficits in dominantly inherited olivopontocerebellar atrophy. Brain Cogn 1991; 16: 121–129.CrossRefGoogle ScholarPubMed
8. Hirono, N, Yamadori, N, Kameyama, M, Mezaki, T and Abe, K. Spinocerebellar degeneration (SCD): cognitive disturbances. Acta Neurol Scand 1991; 84: 226–230.CrossRefGoogle ScholarPubMed
9. Botez, MI. The neuropsychology of the cerebellum: an emerging concept. Arch Neurol 1992; 49: 1229–1230.Google Scholar
10. Botez-Marquard, T and Botez, MI. Cognitive behavior in heredodegenerative ataxias. Eur Neurol 1993; 33: 351–357.CrossRefGoogle ScholarPubMed
11. Grafman, J, Litvan, I, Massaquoi, S, et al. Cognitive planning deficit in patients with cerebellar atrophy. Neurology 1992; 42: 1493–1496.CrossRefGoogle ScholarPubMed
12. Wallesch, CW and Horn, A. Long-term effects of cerebellar pathology on cognitive functions. Brain Cogn 1990; 14: 19–25.Google Scholar
13. Akshoomoff, NA, Courchesne, E, Press, GA and lragui, V. Contribution of the cerebellum to neuropsychological functioning: evidence from a case of cerebellar degenerative disorder. Neuropsychologia 1992; 30: 315–338.CrossRefGoogle ScholarPubMed
14. Fiez, JA, Petersen, SE, Cheney, MK and Raichle, ME. Impaired non-motor learning and error detection associated with cerebellar damage. Brain 1992; 115: 155–178.CrossRefGoogle ScholarPubMed
15. Broich, K, Hartmann, A, Biersack, HJ and Horn, R. Crossed cerebellocerebral diaschisis in a patient with cerebellar infarction. NeurosciLett 1987; 83:7–12.Google Scholar
16. Botez, MI, Léveillé, J, Lambert, R and Botez, T. Single photon emission computed tomography (SPECT) in cerebellar disease: cerebello-cerebral diaschisis. Eur Neurol 1991; 31:405–412.Google Scholar
17. Amrani, K, Pellerin, JP and Lamarre, Y. The effect of bilateral lesions of the cerebellar nuclei on motor performance in the monkey. Soc Neurosci Abstr 1988; 13: 1239.Google Scholar