Hostname: page-component-77c89778f8-vpsfw Total loading time: 0 Render date: 2024-07-19T01:10:48.907Z Has data issue: false hasContentIssue false
  • English
  • Français

Clinical and psychosocial factors affecting treatment adherence in children with rheumatic heart disease

Published online by Cambridge University Press:  06 July 2022

Fatos Alkan Open the ORCID record for Fatos Alkan [Opens in a new window] ,
Ecem Yigit ,
Sermin Yalın Sapmaz  and
Senol Coskun
Fatos Alkan*
Affiliation:
Celal Bayar University, School of Medicine, Department of Pediatrics, Division of Pediatrics Cardiology, Manisa, Turkey
Ecem Yigit
Affiliation:
Celal Bayar University, School of Medicine, Department of Pediatrics, Manisa, Turkey
Sermin Yalın Sapmaz
Affiliation:
Celal Bayar University, School of Medicine, Division of Child and Adolescent Psychiatry, Manisa, Turkey
Senol Coskun
Affiliation:
Celal Bayar University, School of Medicine, Department of Pediatrics, Division of Pediatrics Cardiology, Manisa, Turkey
*
Author for correspondence: Dr. Fatos Alkan, Celal Bayar University, Medical Faculty, Department of Pediatric, Division of Pediatric Cardiology, 45030, Manisa, Turkey. Tel: +90-(236)-444 4228; Fax: +90-(236)-233 8040. E-mail: fatos.alkan@hotmail.com
Get access Rights & Permissions [Opens in a new window]

Abstract

Introduction:

The present study aimed to investigate the outcomes of psychiatric symptoms and family functions on treatment adherence in children, in addition to sociodemographic characteristics and clinical factors related to the disease.

Material and Method:

The research sample consisted of 43 children who were followed up with rheumatic heart disease diagnosis during the study. Clinical features were obtained from the patient files. The family assessment device evaluating family functioning and the strengths and difficulties questionnaire scale to screen emotional and behavioural problems in children were used.

Results:

Considering the regularity of treatment in our patients, there were 31 (72%) patients adherent to secondary prophylaxis regularly, 7 (6.9%) patients were partially adherent, and 5 (11.6%) patients non-adherent. Patients were divided into treatment adherent (Group 1) and non-adherent (Group 2). There was no statistically significant impact on treatment adherence whether the patients receive enough information, lifestyle, fear of developing adverse effects, fear of addiction, lack of health insurance, difficulties in reaching the drug or hospital. However, the fear of syringes on treatment adherence had an effect statistically significantly (p = 0.047). Forgetting to get a prescription and/or take the drug when the time comes was statistically higher in the non-adherent group (p = 0.009). There was no statistically significant effect of psychosocial factors on treatment adherence between groups.

Discussion:

Providing an effective active recall system, involving primary care workers, providing training on the disease and its management, and a comprehensive pain management programme can improve the process, especially for cases where secondary prophylaxis is missed.

Keywords

Rheumatic heart diseasepsychosocial factorstreatment adherence
Type
Original Article
Information
Cardiology in the Young , Volume 32 , Issue 10 , October 2022 , pp. 1668 - 1674
Check for updates
Copyright
© The Author(s), 2022. Published by Cambridge University Press

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Carapetis, JR, McDonald, M, Wilson, NJ. Acute rheumatic fever. Lancet 2005; 366: 155–166.CrossRefGoogle ScholarPubMed
World Health Organisation. Rheumatic Fever and Rheumatic Heart Disease: Report of a WHO Expert Consultation. World Health Organisation, Geneva, 2004.Google Scholar
Lue, HC, Wu, MH, Wang, JK, Wu, FF, Wu, YN. Long-term outcome of patients with rheumatic fever receiving benzathine penicillin G prophylaxis every three weeks versus every for weeks. J Pediatr 1994; 125: 812–816.CrossRefGoogle ScholarPubMed
Cassidy, JT, Petty, RE, Laxer, R, Lindsley, CB. Textbook of Pediatric Rheumatology. 6th edn. Saunders Elsevier, Philadelphia, 2011.Google Scholar
Pinquart, M, Shen, Y. Anxiety in children and adolescents with chronic physical illnesses: a meta-analysis. Acta Paediatr 2011a; 100: 1069–1076.CrossRefGoogle ScholarPubMed
Pinquart, M, Shen, Y. Behavior problems in children and adolescents with chronic physical illness: a metaanalysis. J Pediatr Psychol 2011b; 36: 1003–1016.CrossRefGoogle Scholar
Pinquart, M, Shen, Y. Depressive symptoms in children and adolescents with chronic physical illness: an updated meta-analysis. J Pediatr Psychol 2011c; 36: 375–384.CrossRefGoogle ScholarPubMed
Mackner, LM, Crandall, WV. Oral medication adherence in pediatric inflammatory bowel disease. Inflamm Bowel Dis. 2005; 11: 1006–1012.CrossRefGoogle ScholarPubMed
Kongkaew, C, Jampachaisri, K, Chaturongkul, CA, Scholfield, CN. Depression and adherence to treatment in diabetic children and adolescents: a systematic review and meta-analysis of observational studies. Eur J Pediatr 2014; 173: 203–212.CrossRefGoogle ScholarPubMed
Psihogios, AM, Fellmeth, H, Schwartz, LA, Barakat, LP. Family functioning and medical adherence across children and adolescents with chronic health conditions: a meta-analysis. J Pediatr Psychol 2019;44: 84–97.CrossRefGoogle ScholarPubMed
Dajani, AS, Ayoub, E, Bierman, FZ. Guidelines for the diagnosis of rheumatic fever. Jones Criteria, 1992 update. Special Writing Group of the Committee on Rheumatic Fever, Endocarditis, and Kawasaki Disease of the Council on Cardiovascular Disease in the Young of the American Heart Association. JAMA 1992; 268: 2069–2073.CrossRefGoogle Scholar
Gewitz, M, Baltimore, R, Tani, L, et al. Revision of the Jones Criteria for the diagnosis of acute rheumatic fever in the era of doppler echocardiography: a scientific statement from the American Heart Association. Circulation 2015; 131: 1806–1818.CrossRefGoogle Scholar
Guide for use of echocardiography in acute rheumatic fever. www.nhf.org.nz/files/ Google Scholar
Kevat, PM, Reeves, BM, Ruben, AR, Gunnarsson, R. Adherence to secondary prophylaxis for acute rheumatic fever and rheumatic heart disease: a systematic review. Curr Cardiol Rev. 2017; 13: 155–166.CrossRefGoogle ScholarPubMed
Goodman, R. The strengths and difficulties questionnaire: a research note. J Child Psychol Psychiatry 1997; 38: 581–586.CrossRefGoogle ScholarPubMed
Güvenir, T, Özbek, A, Baykara, B, Arkar, A, Şentürk, B, İncekaş, S. Güçler ve Güçlükler Anketi’nin (GGA) Türkçe uyarlamasının psikometrik özellikleri. Çocuk ve Gençlik Ruh Sağlığı Dergisi 2008; 15: 65–74.Google Scholar
Epstein, NB, Bolwin, LM, Bishop, DS. The MacMaster family assessment device. J Marital Fam Ther 1983; 9: 171–180.CrossRefGoogle Scholar
Bulut, I. Aile Değerlendirme Ölçeği El Kitabı. Öz Güzeliş Matbaası, Ankara, 1990, 1–38.Google Scholar
Mota, CC, Meira, ZMA, Graciano, RN, Graciano, FF, Araujo, FD. Rheumatic fever prevention program: long-term evolution and outcomes. Front Pediatr 2015; 2: 1–5.CrossRefGoogle ScholarPubMed
Pelajo, CF, Lopez-Benitez, JM, Torres, JM, de Oliveira, SK. Adherence to secondary prophylaxis and disease recurrence in 536 Brazilian children with rheumatic fever. Pediatr Rheumatol Online J 2010; 8: 22–26.CrossRefGoogle ScholarPubMed
Spinetto, H, Lennon, D, Horsburgh, M. Rheumatic fever recurrence prevention: a nurse-led programme of 28-day penicillin in an area of high endemnicity. J Paediatr Child Health 2011; 47: 22–234.CrossRefGoogle Scholar
Camara, EJN, Santos, JM, Alves-Silva, LS, Latado, AL. Rheumatic fever recurrence: risk factors and clinical characteristics. Clin Trials Regul Sci Cardiol 2016; 19: 5–8.CrossRefGoogle Scholar
Eissa, S, Lee, R, Binns, P, Garstone, G, McDonald, M. Assessment of a register-based rheumatic heart disease secondary prevention program in an Australian Aboriginal community. Aust N Z J Public Health 2005; 29: 521–525.CrossRefGoogle Scholar
Stewart, T, McDonald, R, Currie, B. Acute rheumatic fever: adherence to secondary prophylaxis and follow up of Indigenous patients in the Katherine region of the Northern Territory. Aust J Rural Health 2007; 15: 234–240.CrossRefGoogle ScholarPubMed
Bassili, A, Zaher, SR, Zaki, A, Abdel-Fattah, M, Tognoni, G. Profile of secondary prophylaxis among children with rheumatic heart disease in Alexandria, Egypt. East Mediterr Health J 2000; 6: 437–446.CrossRefGoogle ScholarPubMed
Mincham, CM, Toussaint, S, Mak, DB, Plant, AJ. Patient views on the management of rheumatic fever and rheumatic heart disease in the Kimberley: a qualitative study. Aust J Rural Health 2003; 11: 260–265.CrossRefGoogle ScholarPubMed
Kumar, R, Raizada, A, Aggarwal, AK, Ganguly, NK. A communitybased rheumatic fever/rheumatic heart disease cohort: twelve-year experience. Indian Heart J 2002; 54: 54–58.Google Scholar
Kumar, R, Thakur, JS, Aggarwal, A, Ganguly, NK. Adherence of secondary prophylaxis for controlling rheumatic fever and rheumatic heart disease in a rural area of northern India. Indian Heart J 1997; 49: 282–288.Google Scholar
Gasse, B, Baroux, N, Rouchon, B, Meunier, JM, Fremicourt, ID, D’Ortenzio, E. Determinants of poor adherence to secondary antibiotic prophylaxis for rheumatic fever recurrence on Lifou, New Caledonia: a retrospective cohort study. BMC Public Health 2013; 13: 131.CrossRefGoogle ScholarPubMed
Harrington, Z, Thomas, DP, Currie, BJ, Bulkanhawuy, J. Challenging perceptions of non-adherence to rheumatic fever prophylaxis in a remote Aboriginal community. Med J Aust 2006; 184: 514–517.CrossRefGoogle Scholar
Robertson, KA, Volmink, JA, Mayosi, BM. Lack of adherence to the national guidelines on the prevention of rheumatic fever. S Afr Med J 2005; 95: 52–56.Google Scholar
Leroy, P, Costa, L, Emmanouil, D, van Beukering, A, Franck, LS. Beyond the drugs: nonpharmacologic strategies to optimize procedural care in children. Curr Opin Anaesthesiol 2016; 29: 1–13.CrossRefGoogle ScholarPubMed
RHDAustralia (ARF/RHD writing group). The 2020 Australian Guideline for Prevention, Diagnosis and Management of Acute Rheumatic Fever and Rheumatic Heart Disease, 3rd edn. 2020.Google Scholar
Hartling, L, Milne, A, Foisy, M, et al. What works and what’s safe in pediatric emergency procedural sedation: an overview of reviews. Acad Emerg Med 2016; 23: 519–530.CrossRefGoogle Scholar
Rosina, R, Crisp, J, Steinbeck, K. Treatment adherence of youth and young adults with and without a chronic illness. Nurs Health Sci 2003; 5: 139–147.CrossRefGoogle Scholar
McClellan, CB, Cohen, LL. Family functioning in children with chronic illness compared with healthy controls: a critical review. J Pediatr 2007; 150: 221–223.CrossRefGoogle ScholarPubMed