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Epidemiological analysis of neonatal CHD near Petrochemical Complex

Published online by Cambridge University Press:  27 November 2019

Ye Chen Open the ORCID record for Ye Chen [Opens in a new window]  and
Lei-Jun Huang
Ye Chen
Affiliation:
Department of Pediatrics, Jinshan Hospital of Fudan University, Jinshan District, Shanghai201508, China
Lei-Jun Huang*
Affiliation:
Echocardiography Room, Jinshan Hospital of Fudan University, Jinshan District, Shanghai201508, China
*
Author for correspondence: L.J. Huang, Echocardiography Room, Jinshan Hospital of Fudan University, 1508 Longhang Road, Jinshan District, Shanghai 201508, China. Tel: +86-21-34189990-5232; E-mail: 2974541962@qq.com
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Abstract

Objective:

To study the incidence, types, and characteristics of CHD in all live births delivered in Jinshan Hospital from 1 January, 2016 to 31 December, 2017, and to analyse the correlation between CHD and the distance between maternal residence and Shanghai Petrochemical Complex.

Methods:

All live births, delivered in Jinshan Hospital in 2016 and 2017, have received CHD screening and neonatal follow-up after delivery. For those both positive for CHD screening and negative for CHD screening but with heart murmur found during physical examination on neonatal follow-up after delivery, echocardiography was performed to confirm CHD diagnosis. All maternal residential addresses have been grouped for analysis according to the distance between maternal residence and Shanghai Petrochemical Complex.

Results:

There were 5544 live births in total, and a total of 79 children with CHD were confirmed by CHD screening and echocardiography, of which the types of diseases with high incidence, in descending order of incidence, are atrial septal defect (48/79), ventricular septal defect (25/79), patent ductus arteriosus (21/79), and pulmonary artery stenosis (9/79). There was no statistically significant difference in the incidence of CHD among the groups divided by the distance between maternal residence and Shanghai Petrochemical Complex. The incidence of neonatal CHD near Shanghai Petrochemical Complex is 1.42%.

Conclusions:

Most of the children with CHD can be screened out through CHD screening and physical examination in neonatal period and early infancy stage. The distance between maternal residence and Shanghai Petrochemical Complex has no significant direct effect on the incidence of CHD in neonates near Shanghai Petrochemical Complex.

Keywords

NeonatalCHDscreeningPetrochemical Complexepidemiology
Type
Original Article
Information
Cardiology in the Young , Volume 30 , Issue 2 , February 2020 , pp. 287 - 290
Copyright
© Cambridge University Press 2019

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