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Use of balloon expandable stents in the palliative relief of obstructed right ventricular conduits

Published online by Cambridge University Press:  19 August 2008

Alison M. Hayes
Affiliation:
Department of Pediatrics, Division of Cardiology, and the Variety Club Cardiac Catheterization, University of Toronto School of Medicine, The Hospital for Sick Children, Toronto, Canada
David G. Nykanen
Affiliation:
Department of Pediatrics, Division of Cardiology, and the Variety Club Cardiac Catheterization, University of Toronto School of Medicine, The Hospital for Sick Children, Toronto, Canada
Brian W. McCrindle
Affiliation:
Department of Pediatrics, Division of Cardiology, and the Variety Club Cardiac Catheterization, University of Toronto School of Medicine, The Hospital for Sick Children, Toronto, Canada
Jeffrey F. Smallhorn
Affiliation:
Department of Pediatrics, Division of Cardiology, and the Variety Club Cardiac Catheterization, University of Toronto School of Medicine, The Hospital for Sick Children, Toronto, Canada
Robert M. Freedom
Affiliation:
Department of Pediatrics, Division of Cardiology, and the Variety Club Cardiac Catheterization, University of Toronto School of Medicine, The Hospital for Sick Children, Toronto, Canada
Lee N. Benson*
Affiliation:
Department of Pediatrics, Division of Cardiology, and the Variety Club Cardiac Catheterization, University of Toronto School of Medicine, The Hospital for Sick Children, Toronto, Canada
*
Dr LN Benson, Division of Cardiology, Hospital for Sick Children, 555 University Avenue, Toronto, Ontario, Canada M5G 1X8. Tel 416 813 6141, Fax: 416 813 7547

Abstract

Objectives

The purpose of this study was to determine the efficacy of balloon expandable stents in the relief of obstructed conduits in the right heart, and to review both the immediate success and longevity of this palliation.

Methods and results

Endovascular stents where placed in 17 children, median age 4.7 yrs (range 0.46–16.2 yrs), at a median of 1.6 yrs (range 0.33–6.7 yrs) after placement of conduits at surgery. A second stent was required in two children, either because of migration of the initial stent or residual proximal stenosis. Mean right ventricular to systemic pressure ratios were reduced from 0.77 ±0.24 to 0.50±0.13, and the minimum area of the pulmonary outflow tract increased from 24±12% to 69±26% of that expected for body surface area. Further surgery was needed in 8 patients following placement of the stent, in 5 within 10 months of implantation, due to inadequate relief of obstruction. Nonetheless, 3 of these 8 children achieved satisfac­tory palliation 18, 21 and 24 months prior to requiring insertion of a new conduit. Actuarial freedom from reoperation was 44% at 24 months. The remaining 9 children continue to benefit from the relief in obstruction provided by the stent at a mean interval from implantation of 24±8 months. In this group, the mean Doppler gradient across the right ventricular outflow tract was 35 ±13 mmHg (n=6).

Conclusions

These early data indicate that endovascular stents are useful in the palliation of obstructed right ventricular conduits. In the short-term, the relief of obstruction achieved is well maintained, and has either delayed or obviated the need for insertion of new conduits.

Type
Brief-Reports
Copyright
Copyright © Cambridge University Press 1997

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