Hostname: page-component-848d4c4894-cjp7w Total loading time: 0 Render date: 2024-06-28T00:32:46.696Z Has data issue: false hasContentIssue false

Brain natriuretic peptide level in a small series of children and grown-ups with congenital heart defects with chronic cardiac failure

Published online by Cambridge University Press:  09 July 2012

Giorgia Grutter*
Affiliation:
Cardiology and Cardiac Surgery Department, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy
Sara Alfieri
Affiliation:
Cardiology and Cardiac Surgery Department, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy
Francesco Parisi
Affiliation:
Cardiology and Cardiac Surgery Department, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy
*
Correspondence to: Dr G. Grutter, Cardiology and Cardiac Surgery Department, Bambino Gesù Children's Hospital, IRCCS, Piazza Sant' Onofrio 4, 00100 Rome, Italy. Tel: +30 06 68593731; Cell: +39 3395450030; Fax: +39 06 68592607; E-mail: giorgiagrutter@libero.it

Abstract

The present study assessed the usefulness of brain natriuretic peptide in evaluating the cardiovascular status in children and grown-ups with congenital or acquired disease affected by chronic cardiac failure. Brain natriuretic peptide should be included in the risk stratification of children with dilated cardiomyopathy. In patients with congenital heart defects, it is useful to tailor the optimal medical strategy to individual patients.

Type
Brief Reports
Copyright
Copyright © Cambridge University Press 2012 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1. Law, YM, Hoyer, AW, Reller, MD, Silberbach, M. Accuracy of plasma B-type natriuretic peptide to diagnose significant cardiovascular disease in children. J Am Coll Cardiol 2009; 54: 14671475.CrossRefGoogle ScholarPubMed
2. Mir, TS, Flato, M, Falkenberg, J, et al. Plasma concentrations of N terminal brain natriuretic peptide in healthy children, adolescents, and young adults: effect of age and gender. Pediatr Cardiol 2006; 27: 7377.Google Scholar
3. Law, YM, Keller, BB, Feingold, BM, Boyle, GJ. Usefulness of plasma B-type natriuretic peptide to identify ventricular dysfunction in paediatric and adult patients with congenital heart disease. Am J Cardiol 2005; 95: 474478.Google Scholar
4. Book, WM, Hott, BJ, McConnell, M. B-type natriuretic peptide levels in adults with congenital heart disease and right ventricle failure. Am J Cardiol 2005; 95: 545546.Google Scholar
5. Harrison, A, Morrison, L, Krishnaswamy, P, et al. B-type natriuretic peptide predicts future cardiac events in patients presenting to the emergency department with dyspnea. Ann Emerg Med 2002; 39: 131138.Google Scholar
6. Lin, NC, Landt, ML, Trinkaus, KM, Balzer, DT, Kort, HW, Canter, CE. Relation of age, severity of illness, and hemodynamics with brain natriuretic peptide levels in patients < 20 years of age with heart disease. Am J Cardiol 2005; 96: 847850.Google Scholar
7. Law, YM, Keller, BB, Feingold, BM, Boyle, GJ. Usefulness of plasma B-type natriuretic peptide to identify ventricular dysfunction in pediatric and adult patients with congenital heart disease. Am J Cardiol 2005; 95: 474478.Google Scholar
8. Mir, TS, Marohn, S, Läer, S, Eiselt, M, Grollmus, O, Weil, J. Plasma concentrations of N-terminal pro-brain natriuretic peptide in control children from the neonatal to adolescent period and in children with congestive heart failure. Pediatrics 2002; 110: e76.Google Scholar
9. Giannakoulas, G, Dimopoulos, K, Bolger, AP, et al. Usefulness of natriuretic peptide levels to predict mortality in adults with congenital heart disease. Am J Cardiol 2010; 105: 869873.CrossRefGoogle ScholarPubMed
10. Koch, A, Zink, S, Singer, H. B-type natriuretic peptide in paediatric patients with congenital heart disease. Eur Heart J 2006; 27: 861866.Google Scholar