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Echocardiographic assessment of left ventricular dyssynchrony in Egyptian children with congestive heart failure due to dilated cardiomyopathy

Published online by Cambridge University Press:  02 October 2014

Mohammed A. Al-Biltagi Open the ORCID record for Mohammed A. Al-Biltagi [Opens in a new window] ,
Osama Abd Rab Elrasoul Tolba ,
Heba El Mahdy ,
Amr Donia  and
Shaimaa Elbanna
Mohammed A. Al-Biltagi*
Affiliation:
Pediatric Department, Faculty of Medicine, Tanta University, Tanta, Egypt
Osama Abd Rab Elrasoul Tolba
Affiliation:
Pediatric Department, Faculty of Medicine, Tanta University, Tanta, Egypt
Heba El Mahdy
Affiliation:
Pediatric Department, Faculty of Medicine, Tanta University, Tanta, Egypt
Amr Donia
Affiliation:
Pediatric Department, Faculty of Medicine, Tanta University, Tanta, Egypt
Shaimaa Elbanna
Affiliation:
Pediatric Department, Faculty of Medicine, Tanta University, Tanta, Egypt
*
Correspondence to: M. A. Al-Biltagi, MD, PhD (Pediatric), Pediatric Cardiology Unit, Department of Pediatrics, Faculty of Medicine, Tanta University, Tanta, Egypt. Tel: 0020102209797; Fax: 020402213543; E-mail: mbelrem@hotmail.com
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Abstract

Objective: To evaluate the presence of cardiac dyssynchrony in Egyptian children with congestive heart failure due to dilated cardiomyopathy. Materials and methods: A total of 30 children with congestive cardiac failure due to dilated cardiomyopathy and 30 healthy age-matched controls were examined with conventional echocardiography, tissue Doppler, and speckle tracking imaging. Results: Conventional Doppler echocardiography demonstrated significant left ventricular systolic and diastolic dysfunction in the patient group. Tissue Doppler showed significant decrease in S-wave velocity and E'/A' ratio, and prolonged isovolumic contraction and relaxation times of mitral annulus as well as significant prolongation in mean difference between time-to-peak systolic strain of the basal septal and basal lateral segments in the patient group compared with the control group (p<0.005). Speckle tracking imaging demonstrated significant prolongation in mean difference between time-to-peak systolic strain of anteroseptal and posterior segments in both circumferential and radial strain analysis in the patient group than in the control group (p<0.005). It also demonstrated significant prolongation in the mean difference between time-to-peak systolic strain of the basal septal and basal lateral segments in longitudinal strain analysis in the patient group than in the control group (p<0.005). A significant increase in the standard deviation of time-to-peak strain, as a marker of increased intra-ventricular dyssycnrony, was present in the patient group compared with the control group (p=0.008). Conclusion: Children with congestive heart failure due to dilated cardiomyopathy usually suffer from significant intra-ventricular dyssynchrony. Tissue Doppler imaging and speckle tracking imaging strain analysis are helpful tools to detect the presence of cardiac dyssynchrony.

Keywords

Dilated cardiomyopathycardiac dyssynchronychildrenspeckle tracking imagingtissue Doppler imaging
Type
Original Articles
Information
Cardiology in the Young , Volume 25 , Issue 6 , August 2015 , pp. 1173 - 1181
Copyright
© Cambridge University Press 2014 

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