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Pharmacologic therapy with flecainide for asymptomatic Wolff–Parkinson–White syndrome in an infant with severe left ventricular dyssynchrony

Part of: Electrophysiology

Published online by Cambridge University Press:  31 May 2018

Sayo Suzuki ,
Tatsunori Hokosaki  and
Mari Iwamoto
Sayo Suzuki*
Affiliation:
Department of Pediatric Cardiology, Yokohama City University Hospital, Fukuura 3-9, Kanazawa-ku, Yokohama city, Kanagawa 236-0004, Japan
Tatsunori Hokosaki
Affiliation:
Department of Pediatric Cardiology, Yokohama City University Hospital, Fukuura 3-9, Kanazawa-ku, Yokohama city, Kanagawa 236-0004, Japan
Mari Iwamoto
Affiliation:
Department of Pediatric Cardiology, Yokohama City University Hospital, Fukuura 3-9, Kanazawa-ku, Yokohama city, Kanagawa 236-0004, Japan
*
Author for correspondence: S. Suzuki. Department of Pediatric Cardiology, Yokohama City University Hospital, Fukuura 3-9, Kanazawa-ku, Yokohama city, Kanagawa 236-0004, Japan. Tel: +81 45 787 2800, E-mail: passayo346@hotmail.co.jp
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Abstract

Some asymptomatic patients with Wolff–Parkinson–White syndrome have severe left ventricular dyssynchrony and dysfunction. We describe a patient who was given a diagnosis of Wolff–Parkinson–White syndrome in infancy and had a complete response to pharmacologic therapy with flecainide. Our findings suggest that flecainide is a suitable resynchronisation therapy for such infants.

Keywords

Wolff–Parkinson–White syndromeleft ventricular dyssynchronyresynchronisation therapyflecainide
Type
Brief Report
Information
Cardiology in the Young , Volume 28 , Issue 7 , July 2018 , pp. 970 - 973
Copyright
© Cambridge University Press 2018 

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References

1. Tomaske, M, Janousek, J, Razek, V, et al. Adverse effects of Wolff-Parkinson-White syndrome with right septal or posteroseptal accessory pathways on cardiac function. Europace 2008; 10: 181–1892.Google Scholar
2. Kwon, BS, Bae, EJ, Kim, GB, et al. Septal dyskinesia and global left ventricular dysfunction in pediatric Wolff-Parkinson-White syndrome with septal accessory pathway. J Cardiovasc Electrophysiol 2010; 21: 290–295.Google Scholar
3. Kwon, E, Carter, K, Carter, J, et al. Radiofrequency catheter ablation for dyssynchrony-induced dilated cardiomyopathy in an infant. Congenit Heart Dis 2014; 9: E179–E184.Google Scholar
4. Cadrin-Tourigny, J, Fournier, A, Andelfinger, G, et al. Severe left ventricular dysfunction in infants with ventricular preexcitation. Heart Rhythm 2008; 5: 1320–1322.Google Scholar
5. Peach, C, Flosdorff, P, Gebauer, RA, et al. Pharmacologic cardiac resynchronization of 1-year-old boy with severe left ventricular dysfunction. Pediatr Cardiol 2012; 33: 1213–1215.Google Scholar
6. Friedman, RA, Walsh, EP, Silka, MJ, et al. NAPSE Expert Consensus Conference: radiofrequency catheter ablation in children with and without congenital heart disease: report of the writing committee. North American Society of Pacing and Electrophysiology. Pacing Clin Electrophysiol 2002; 25: 1000–1017.Google Scholar
7. Suzuki, Y, Suzuki, T, Inuzuka, R, et al. An infant with heart failure due to ventricular dyssynchrony and refractory tachycardia caused by a right anterolateral accessory pathway. Cardiology 2012; 123: 108–112.Google Scholar
8. Kim, SH, Jeong, SI, Huh, J, et al. Amiodarone and catheter ablation as cardiac resynchronization therapy for children with dilated cardiomyopathy and Wolff-Parkinson-White syndrome. Korean Circ J 2013; 43: 57–61.Google Scholar
9. Fazio, G, Mongiovi, M, Sutera, L, et al. Segmental dyskinesia in Wolff–Parkinson–White syndrome: A possible cause of dilative cardiomyopathy. Int J Cardiol 2008; 123: e31–e34.Google Scholar
10. Bosser, G, Marcon, F, Lethor, JP, et al. Long-term efficacy and tolerability of amiodarone in children. Arch Mal Coeur Vaiss 1995; 88: 731–736.Google Scholar