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Staged reconstructive surgery – the most appropriate therapy for hypoplastic left heart syndrome

Published online by Cambridge University Press:  21 September 2005

Marshall L. Jacobs
Marshall L. Jacobs
Affiliation:
Department of Cardiothoracic Surgery, Drexel University College of Medicine, St. Christopher's Hospital for Children, Philadelphia, USA
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Extract

I am grateful for the opportunity to participate in this debate forum, and for the honor of exchanging concepts with Len Bailey. This debate, fortunately, represents a “win-win” situation. The innovations and evolution of both replacement of the heart and reconstructive surgery for hypoplastic left heart syndrome are stories with lots of winners. The entire field of transplantation biology, the entire scope of management of the newborn with complex congenital heart disease, including both medical and supportive therapy and surgical strategies, has each been advanced tremendously as a consequence of the introduction and refinement of these two very different therapies for hypoplastic left heart syndrome. So, it is a debate that cannot be lost.

Type
Debates
Information
Cardiology in the Young , Volume 14 , Issue S1 , February 2004 , pp. 105 - 108
Copyright
© 2004 Cambridge University Press

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References

Jacobs ML, Blackstone EG, Bailey LL. Intermediate survival in neonates with aortic atresia: a multi-institutional study. The Congenital Heart Surgeons Society. J Thorac Cardiovasc Surg 1998; 116: 417–431.Google Scholar
Austin EH 3rd. Postoperative management after the Norwood procedure. Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu 1998; 1: 109–122.Google Scholar
Migliavacca F, Pennati G, Dubini G, Fumero R, Pietrabissa R, Urcelay C, Bove EL, Hsia Ty, de Leval MR. Modeling of the Norwood circulation: effects of shunt size, vascular resistances, and heart rate. Am J Physiol Heart Circ Physiol 2001; 280: H2076–H2086.Google Scholar
Hoffman GM, Ghanayem NS, Kampine JM, Berger S, Mussatto KA, Litwin SB, Tweddell JS. Venous saturation and the anaerobic threshold in neonates after the Norwood procedure for hypoplastic left heart syndrome. Ann Thorac Surg 2000; 70: 1515–1520; discussion 1521.Google Scholar
Mahle WT, Spray TL, Wernovsky G, Gaynor JW, Clark BJ 3rd. Survival after reconstructive surgery for hypoplastic left heart syndrome: A 15-year experience from a single institution. Circulation 2000; 102 (19 Suppl 3): III36–III41.Google Scholar
Mahle WT, Rychik J, Weinberg PM, Cohen MS. Growth characteristics of the aortic arch after the Norwood operation. J AM Coll Cardiol 1998; 32: 1951–1954.Google Scholar
Mahle WT, Clancy RR, Moss EM, Gerdes M, Jobes DR, Wernovsky G. Neurodevelopmental outcome and lifestyle assessment in school-aged and adolescent children with hypoplastic left heart syndrome. Pediatrics 2000; 105: 1082–1089.Google Scholar
Goldberg CS, Schwartz EM, Brunberg JA, Mosca RS, Bove EL, Schork MA, Stetz SP, Cheatham JP, Kulik TJ. Neurodevelopmental outcome of patients after the Fontan operation: A comparison between children with hypoplastic left heart syndrome and other functional single ventricle lesions. J Pediatr 2000; 137: 646–652.Google Scholar