The COVID-19 has brought double pressure on the work and psychology of innovation and entrepreneurship personnel, which is prone to anxiety. Positive psychology can promote the all-round development of human body and mind. Therefore, under the epidemic environment, the research uses positive psychology to intervene and treat the psychological diseases of innovative and entrepreneurial personnel, and alleviate their psychological anxiety.

The study randomly selected 128 people who will carry out innovation and entrepreneurship from 2021 to 2022. The study used positive psychology to intervene 128 people, and judged their mental health status through their work enthusiasm and psychological resilience. In the experiment, P < 0.05 indicates that the difference is statistically significant, and t-test is conducted. After the experiment, SPSS21.0 was used for statistical analysis of the data. The experimental results are shown in Table 1.Table 1.

Changes in work enthusiasm and resilience of innovation and entrepreneurship personnel before and after intervention

Before the intervention, the self-assessment result of innovation and entrepreneurship personnel’s work enthusiasm was 5.27 ± 0.45 points, and the mutual evaluation result was 7.91 ± 0.42 points; After intervention, it was 7.91 ± 0.42 points and 9.10 ± 0.36 points. At the same time, after the intervention, the scores of three indicators in the scores of employees’ resilience level have increased. To sum up, positive psychology has effectively alleviated the psychological anxiety of innovation and entrepreneurship personnel. In addition, P < 0.001 indicates that the difference of the study has statistical significance.

The external environment of innovation and entrepreneurship in the context of the COVID-19 has gradually become worse, which has brought a lot of psychological pressure to innovation and entrepreneurship personnel, thus causing psychological diseases. The study used positive psychology to intervene, and the experimental results showed that positive psychological coping intervention for innovative entrepreneurs during the COVID-19 epidemic could effectively alleviate their psychological anxiety.

The research is supported by: the Key Construction Base of Philosophy and Social Sciences in Jiangsu Province, Research Center of Industrial Transformation and Innovation Development in Southern Jiangsu Province, No. 2018ZDJD-B008.