Mixed-type depression among college students is a common mental health problem. The concept of simultaneous development of the five educations emphasizes comprehensive quality education and has been widely applied in higher education.

Students selected from a university are the research subjects and are divided into an experimental group and a control group. The experimental group received comprehensive quality education that conforms to the concept of simultaneous development of the five educations, including academic education, physical exercise, moral cultivation, artistic cultivation, and social practice; The control group continued to receive traditional academic education. The study collected students’ depression scores and mental health questionnaire survey data as research indicators and used Stata statistical software for data processing and analysis.

The depression scores of the experimental group students significantly decreased. The specific numerical change data shows that the depression score of the experimental group students decreased from the initial 24.5 to 16.3, while the depression score of the control group students decreased from the initial 25.2 to 20.1.

The research results indicate that the concept of combining five educations has a positive effect on college students. The implementation of comprehensive quality education, including academic education, physical exercise, moral cultivation, artistic cultivation, and social practice, can effectively reduce the occurrence and degree of mixed depression among college students.

The graduate education research project of Southwest Jiaotong University in 2020 (No. yjg4-2020-tz03-1).