Informatization has become a key element of modern enterprise management, and managers face severe anxiety in high-pressure work environments, which hurts personal health and organizational performance. It is very important to study the alleviating effect of information-based enterprise management on the anxiety of managers.

SASRQ and 3D-CAM were used to assess management anxiety, and SPSS23.0 was used to collect and analyze data. Through comparative analysis, the study evaluated the effect of information enterprise management on the anxiety of managers and guided decision-making and practice.

In the study, 100 managers were recruited as samples from different information enterprises. SASRQ and 3D-CAM were used to measure the samples, and the results showed that the anxiety symptoms of managers were significantly relieved under the management of information-based enterprises. The average SASRQ score decreased by 27.8% from 75.2 to 54.8. The average 3D-CAM measurement score decreased from 7.3 to 3.6, a decrease of 50.7%. SPSS23.0 statistical analysis results show that information-based enterprise management has a significant effect on the relief of management anxiety (P< 0.001).

The study shows that information enterprise management has a significant effect on management anxiety. Using SASRQ and 3D-CAM as assessment tools, data analysis based on SPSS23.0 showed a significant reduction in manager anxiety symptoms. Therefore, organizations should actively promote the application of information-based enterprise management to improve managers’ mental health and improve organizational performance.