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Vagus nerve stimulation for intractable epilepsy in children

Published online by Cambridge University Press:  01 July 2000

Douglas Labar
Douglas Labar
Affiliation:
Comprehensive Epilepsy Center, New York Presbyterian Hospital-Cornell, New York, USA.
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Abstract

Intermittent electrical stimulation of the cervical vagus nerve (VNS) with an implanted pulse generator is a new adjunctive treatment for severe seizure disorders. In two large, prospective, double-blind randomized controlled trials involving more than 300 patients, VNS reduced seizure rates by 25% within 3 months. A 3-year follow-up study of these and 125 additional patients indicated that efficacy was maintained; seizure rates were reduced by 45%. General reviews on VNS in adults, and mechanisms of action are given by McLachlan and Schachter and Saper.

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Annotation
Information
Developmental Medicine and Child Neurology , Volume 42 , Issue 7 , July 2000 , pp. 496 - 499
Copyright
© 2000 Mac Keith Press

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