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Agglutination of red blood cells of different animal species by influenza and Newcastle disease viruses

Published online by Cambridge University Press:  15 May 2009

C. M. Chu
C. M. Chu
Affiliation:
From the Department of Bacteriology, London School of Hygiene and Tropical Medicine
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The agglutination of red cells of seventeen animal species by influenza and Newcastle disease viruses has been quantitatively investigated. The peculiar behaviour of one group of red cells, illustrated by ox, toward influenza virus heated for 30 min. at 56° C. and toward purified N.D.V. has been studied in detail. It is concluded that heated influenza virus acquires an apparently increased titre against ox cells because it has lost its eluting power. Similarly, purified N.D.V. is less readily eluted from red cells, due to the elimination of an ‘elution-hastening factor’ present in infected fluid. The present study illustrates the importance of careful adjustment of all possible variable conditions for individual viruses and individual red cell systems.

Type
Research Article
Information
Journal of Hygiene , Volume 46 , Issue 3 , September 1948 , pp. 239 - 246
Copyright
Copyright © Cambridge University Press 1948

References

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