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The Agglutination of Standard Agglutinable Cultures of the Flexner-group of Dysentery Bacilli by Non-dysenteric Human Sera

Published online by Cambridge University Press:  15 May 2009

A. D. Gardner
A. D. Gardner
Affiliation:
From the Standards Laboratory (Medical Research Council), Department of pathology, University of Oxford.
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1. The results are recorded of the degrees to which standard agglutinable cultures of five serological types Flexner-group bacilli (V, W, X, Y, Z) are agglutinated by non-dysenteric human sera.

2. Certian of these cultures are more highly agglutinated by some normal human sera than was anticipated.

3. In order that the sera of non-dysenteric subjects may all (or parctically all) be found to contain less than 10 or less than 20 units in males and females respectively, the reduction-factors of agglutinability at persent in use for certain of these cultures must be somewhat increased.

4. The conception of a limit, above which no “normal” serum will be found to react, is only valid as a compromise between truth and convenience. Repetition of agglutination-tests capable of measuring the fluctuation of agglutinins in active infection is the only safe and scientific procedure.

Type
Research Article
Information
Journal of Hygiene , Volume 21 , Issue 4 , August 1923 , pp. 399 - 405
Copyright
Copyright © Cambridge University Press 1923

References

REFERENCES

Andrewes, F.W. and Inman, A.C. (1919). A study of the serological races of the Flexner group of Dysentery bacilli. Medical Research Committee. Specical Reprod Series, No. 42.Google Scholar
Courmont, P. (1897). La courbe agglutinante chez les typhiques. Rev. de méd. p. 745.Google Scholar
Courmont, P. (1900). La courbe agglutinante chez les typhiques. Rev. de méd. p. 317.Google Scholar
Dreyer, G. (1909). Widal's reaction with sterilized cultures. Journ. of Path. and Bact. XIII. 331. Translated from Hospitalstidende, 1906, No.19. Copenhagen.CrossRefGoogle Scholar
Dreyer, G., Ginson, A.G. and Walker, E.W.A. (1916). Further remarks on agglutination tests in inoculated persons. Lancet, P. 241.Google Scholar
Dreyer, G. and Inman, A.C. (1917). The agglutination-ourve and its importancce in the diagnosis of Typhoid and Paratyphoid fevers in inoculated persons. Lancet, March 10.CrossRefGoogle Scholar
Gardner, A.D. (1918). The standardization of killed agglutinable cultures of B. dysenteriae. Journ. of Hygiene. XVII. 471.Google Scholar
Gardner, A.D. (1921). The normal limit of agglutination for B. dysenteriae (Flexner). Lancet, II. 1269.CrossRefGoogle Scholar
Gettings, H.S. (1919). An investigation of the Flexner-Y Group of Dysentery bacilli. Medical Research Council. Special Report Series, No. 30.Google Scholar
Jórgensen, A. (1904). Svingninger i blodets agglutinerende evne ved febris typhoidea. Thesis. Copenhagen.Google Scholar
Kruse, Ritierahaus, Ketz, and Metz, (1907). Dysenterie und Pseudodysenterie. Zeitsch. f. Hyg. 57. 417.CrossRefGoogle Scholar
Martin, C.J., Hartley, P. and Williams, F.E. (1918). Agglutination in the diagnosis of Dysentery. Lancet, I. 642.Google Scholar
Murray, E.G.D. (1918). An attempt at calssification of Bacillus Dysenteriae, etc. Journ. of the Royal Army Mediical Corps, 31. 353.Google Scholar
Pillsbury, L.B. (1903). The degree in which substances agglutinating the Dysentery bacilli are present in the blood of non-infected persons. Med. News, N. Y. LXXIII. 1078.Google Scholar
Schroeder, K. (1909). Om Aareladningens uidflydesepaa Blodets Agglutinin-holdighed. Thesis. Copenhagen.Google Scholar
Walker, Hall I. (1916). Convalesoent Paratyphoidal and Dysenteric cases considered from the preventive Standpoint. Lancet, II. 174.Google Scholar