Hostname: page-component-848d4c4894-p2v8j Total loading time: 0 Render date: 2024-06-09T14:02:46.728Z Has data issue: false hasContentIssue false

Bacterial lysis and antiseptics

Published online by Cambridge University Press:  15 May 2009

R. J. V. Pulvertaft
Affiliation:
From the John Burford Carlill Laboratories, Westminster Hospital School of Medicine
G. D. Lumb
Affiliation:
From the John Burford Carlill Laboratories, Westminster Hospital School of Medicine
Rights & Permissions [Opens in a new window]

Extract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

When a number of organisms are exposed in early rapidly multiplying broth cultures to minimally effective bacteriostatic concentrations of a number of antiseptics, almost complete lysis may be demonstrated.

When older cultures are exposed to low concentrations, or young cultures to strong concentrations, lysis does not occur in many cases.

The lytic effect of penicillin is apparently identical with that of the antiseptics tested. The phenomenon appears to depend on the nature of the effect of the antiseptic on metabolic enzymes, autolytic enzymes, or both.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1948

References

REFERENCES

Dubos, R. J. (1945). The Bacterial Cell, p. 94. Harvard University Press.Google Scholar
Fleming, A. (1929). Brit. J. Exp. Path. 10.Google Scholar
Gratia, A. & Dath, A. (1925). C.R. Soc. Biol., Paris, 92, 461, 1125.Google Scholar
Quastel, J.H. & Wooldridge, W. R. (1927). Biochem.J. 21, 148, 1224.CrossRefGoogle Scholar
Thom, C. (1930). The Penicillia, p. 82. Ballière, Tindall and Cox.Google Scholar
Todd, E. W. (1945). Lancet, pp. 74, 172.CrossRefGoogle Scholar