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Contamination of Apparatus During Freeze-Drying
Published online by Cambridge University Press: 15 May 2009
Extract
When the manifold system of freeze-drying is used the practice of plugging the tubes containing the product to be dried would seem to be necessary. It should be emphasized that a loose plug implies teased out cotton-wool and not just a loosely fitting one. Virus was recovered from the drying apparatus under various conditions when unplugged tubes were used. No virus contamination could be demonstrated when the tubes were plugged.
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- Copyright © Cambridge University Press 1959
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